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Serevent Diskus

Serevent Diskus (salmeterol xinafoate) is a long-acting beta-2 adrenergic agonist (LABA) used in the management of asthma and chronic obstructive pulmonary disease (COPD). It is indicated for the maintenance treatment of these conditions and helps to improve breathing by relaxing the muscles in the airways, making it easier to breathe.


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Frequently Asked Questions

How quickly does Serevent Diskus work?
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Serevent Diskus typically begins to improve lung function within 30 minutes, with peak effects occurring around 2 to 3 hours after inhalation.

Can I use Serevent Diskus while pregnant or breastfeeding?
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Consult your healthcare provider before using Serevent Diskus if you are pregnant, planning to become pregnant, or breastfeeding to assess any potential risks.

Are there any specific dietary restrictions while using Serevent Diskus?
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There are no specific dietary restrictions associated with the use of Serevent Diskus.

What should I do if I miss a dose of Serevent Diskus?
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If you miss a dose, take it as soon as you remember. If it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is Serevent Diskus safe for long-term use?
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Serevent Diskus is generally safe for long-term use in conjunction with inhaled corticosteroids for asthma and COPD management. Regular follow-ups with a healthcare provider are important to monitor effectiveness and any potential side effects.

Comprehensive Drug Guide

How Does Serevent Diskus Work?

  • Stimulating beta-2 adrenergic receptors in the airway smooth muscle: This stimulation leads to relaxation of the bronchial muscles, resulting in bronchodilation (widening of the airways) and improved airflow.

Common Dosages

  • Dry powder inhaler: Each inhalation delivers 50 mcg of salmeterol.

Typical Dosing

  • For asthma: The usual dose is 1 inhalation (50 mcg) twice daily, approximately 12 hours apart.
  • For COPD: The same dosing of 1 inhalation (50 mcg) twice daily is recommended.

Typical Dosing

FDA Approved Indications

  • Maintenance treatment of asthma in patients aged 4 years and older.
  • Maintenance treatment of COPD, including chronic bronchitis and emphysema.

Who Shouldn't Take Serevent Diskus?

  • Known hypersensitivity to salmeterol or any components of the formulation.
  • Acute bronchospasm or as a rescue medication for asthma attacks.

Advice From The Pharmacist

  • Instruct patients on the proper technique for using the Diskus inhaler to ensure effective delivery of the medication.
  • Advise patients to not use Serevent Diskus as a rescue inhaler and to have a short-acting bronchodilator available for acute symptoms.
  • Discuss potential side effects, including headache, palpitations, and muscle cramps, and encourage patients to report any severe or unusual symptoms.

Side Effects of Serevent Diskus

Common Side Effects

  • Headache
  • Nervousness or anxiety
  • Dizziness
  • Muscle cramps

Uncommon/Severe Side Effects

  • Severe allergic reactions (such as rash, itching, or difficulty breathing).
  • Increased risk of asthma-related death when used alone for asthma management.

Risks and Warnings of Serevent Diskus

  • Cardiovascular Effects: Use with caution in patients with a history of cardiovascular disease, as LABAs can cause increased heart rate and blood pressure.
  • Potential for Asthma Exacerbation: LABAs should not be used as monotherapy for asthma; they should always be combined with an inhaled corticosteroid for safety.

Interactions with Serevent Diskus

Common Drug Interactions

  • Other Medications: Patients should inform their healthcare provider about all medications they are taking, particularly other bronchodilators or medications that can affect heart rhythm.

Alternatives to Serevent Diskus

  • Other Asthma and COPD Medications: Alternatives may include short-acting beta-agonists (SABAs) for rescue therapy, inhaled corticosteroids (ICS), or other long-acting bronchodilators depending on individual patient needs.