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Rythmol SR

Rythmol SR (propafenone) is an antiarrhythmic medication used primarily for the treatment of ventricular arrhythmias and atrial fibrillation. It works by stabilizing the heart's electrical activity, helping to restore normal heart rhythm. The "SR" designation stands for "sustained release," indicating that the formulation is designed to release the medication gradually over time.



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Frequently Asked Questions

How quickly does Rythmol SR start to work?
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Patients may start to notice effects on their heart rhythm within a few hours of taking Rythmol SR, but it may take several days to achieve optimal control.

Can I stop taking Rythmol SR suddenly?
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It is important to consult your healthcare provider before stopping Rythmol SR, as abrupt discontinuation can lead to worsening of arrhythmias.

Are there any specific dietary restrictions while using Rythmol SR?
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There are no specific dietary restrictions; however, patients should maintain a balanced diet to support overall health.

What should I do if I miss a dose of Rythmol SR?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is Rythmol SR safe for long-term use?
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Rythmol SR can be safe for long-term use under medical supervision for managing arrhythmias. Regular follow-ups are essential to monitor heart function and overall health.

Comprehensive Drug Guide

How Does Rythmol SR Work?

  • Blocking sodium channels in the cardiac cells, which stabilizes the cardiac cell membrane and slows down conduction in the heart. This action helps to prevent abnormal electrical signals that can lead to arrhythmias.


Common Dosages

  • Sustained-release tablets: Common strengths include 150 mg, 300 mg, and 225 mg.

Typical Dosing

  • The usual starting dose for adults may be 150 mg taken twice daily, which can be adjusted based on the patient's response and tolerability. The maximum recommended dose is typically 300 mg taken twice daily.


Typical Dosing

FDA Approved Indications

  • Management of ventricular arrhythmias
  • Treatment of atrial fibrillation or atrial flutter to restore normal sinus rhythm.


Who Shouldn't Take Rythmol SR?

  • Known hypersensitivity to propafenone or any components of the formulation.
  • Severe heart failure or significant left ventricular dysfunction.
  • Certain types of heart block (unless a pacemaker is present).


Advice From The Pharmacist

  • Instruct patients to take Rythmol SR exactly as prescribed and to avoid sudden discontinuation, as this may exacerbate arrhythmias.
  • Advise patients to monitor for signs of heart-related issues, such as palpitations, dizziness, or chest pain, and to report any severe or concerning symptoms immediately.
  • Discuss potential side effects, including dizziness, fatigue, and gastrointestinal disturbances, and encourage patients to maintain regular follow-up appointments for heart monitoring.


Side Effects of Rythmol SR

Common Side Effects

  • Dizziness or lightheadedness
  • Nausea or vomiting
  • Fatigue
  • Abdominal discomfort
  • Blurred vision


Uncommon/Severe Side Effects

  • Severe allergic reactions (such as rash, itching, or difficulty breathing)
  • New or worsening arrhythmias.


Risks and Warnings of Rythmol SR

  • Cardiac Monitoring: Patients on Rythmol SR should be monitored regularly for cardiac function, particularly during the initial titration and following dose adjustments.
  • Liver Function: Use with caution in patients with liver impairment, as propafenone is metabolized in the liver, and dosage adjustments may be necessary.


Interactions with Rythmol SR

Common Drug Interactions

  • Other Medications: Patients should inform their healthcare provider about all medications they are taking, especially other antiarrhythmics, anticoagulants, or medications that affect liver enzymes, as these can interact with propafenone and affect its efficacy and safety.


Alternatives to Rythmol SR

  • Other Antiarrhythmic Agents: Alternatives may include other antiarrhythmic medications such as flecainide, amiodarone, or sotalol, depending on the specific type of arrhythmia and individual patient needs.