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RotaTeq
RotaTeq is a live attenuated vaccine used to prevent rotavirus gastroenteritis in infants. Rotavirus is a highly contagious virus that causes severe diarrhea, vomiting, fever, and abdominal pain, primarily in babies and young children. RotaTeq is designed to help the body build immunity to rotavirus, significantly reducing the severity of the infection and preventing hospitalizations due to dehydration caused by diarrhea. The vaccine is given orally in a series of doses starting at 6 to 12 weeks of age.
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Frequently Asked Questions
How effective is RotaTeq?
RotaTeq is highly effective in preventing severe rotavirus gastroenteritis, reducing the risk of hospitalization due to rotavirus-related diarrhea by 85% to 98%.
Can RotaTeq cause rotavirus infection?
No, RotaTeq contains weakened (attenuated) virus strains that do not cause full-blown rotavirus infection. However, mild gastrointestinal symptoms such as diarrhea or vomiting may occur after vaccination.
What should I do if my baby misses a dose of RotaTeq?
If your baby misses a scheduled dose, contact your healthcare provider to schedule the next dose as soon as possible. All doses should be completed by 32 weeks of age.
Can RotaTeq be given with other vaccines?
Yes, RotaTeq can be given at the same time as other routine vaccines, such as DTaP, IPV, and Hib vaccines.
How long does immunity from RotaTeq last?
RotaTeq provides long-term protection against severe rotavirus gastroenteritis, although the exact duration of immunity varies. Studies suggest that the vaccine provides protection through the first several years of life, which is when children are most vulnerable to severe rotavirus infection.
Comprehensive Drug Guide
How Does RotaTeq Work?
RotaTeq contains five live attenuated strains of rotavirus that are weakened so they cannot cause severe illness in healthy infants. Once administered orally, the vaccine stimulates the immune system to produce antibodies against rotavirus. These antibodies help the body recognize and fight off future rotavirus infections, thereby reducing the severity of the disease if the child is later exposed to the virus.
Common Dosages
- The first dose should be given between 6 and 12 weeks of age.
- The second dose should be given at least 4 weeks after the first.
- The third dose should be given by 32 weeks of age.
Typical Dosing
- First dose: Administer orally between 6 and 12 weeks of age.
- Second dose: Administer orally at least 4 weeks after the first dose.
- Third dose: Administer orally by 32 weeks of age.
- Each dose consists of 2 mL of oral solution. The vaccine is given directly into the infant’s mouth.
Typical Dosing
FDA Approved Indications
- Prevention of rotavirus gastroenteritis in infants aged 6 to 32 weeks. The vaccine is administered as part of a routine immunization schedule to protect infants from rotavirus infections.
Who Shouldn't Take RotaTeq?
- A history of severe allergic reactions (anaphylaxis) to any component of the vaccine or a previous dose of rotavirus vaccine.
- Infants with a history of intussusception (a condition in which part of the intestine slides into an adjacent part of the intestine).
- Infants with severe combined immunodeficiency (SCID).
Advice From The Pharmacist
- RotaTeq is given orally and should be administered by a healthcare provider as part of the infant's routine vaccination schedule.
- The vaccine should not be injected or given to infants who are already experiencing acute gastrointestinal illness, such as severe diarrhea or vomiting. In these cases, vaccination should be delayed.
- Make sure your infant receives all three doses of the vaccine by the age of 32 weeks for full protection.
- After receiving RotaTeq, the baby may have a mild fever, irritability, or mild gastrointestinal symptoms such as diarrhea or vomiting. These usually resolve on their own.
- After vaccination, wash your hands carefully after changing diapers, as the live virus may be present in the stool for up to 10 days after vaccination.
Side Effects of RotaTeq
Common Side Effects
- Mild diarrhea
- Vomiting
- Fever
- Irritability
Uncommon/Severe Side Effects
- Intussusception (a rare but serious bowel obstruction)
- Severe allergic reactions, including rash, itching, or difficulty breathing
Risks and Warnings of RotaTeq
- Intussusception Risk: There is a small risk of intussusception (a type of bowel blockage) in infants who receive RotaTeq. The highest risk occurs within the first week after the first or second dose. Parents should watch for symptoms such as severe stomach pain, bloody stools, or vomiting, and seek immediate medical attention if these occur.
- Immunocompromised Infants: Infants with weakened immune systems (e.g., those with SCID) should not receive RotaTeq, as the live virus could cause serious illness.
Interactions with RotaTeq
Common Drug Interactions
- Other vaccines: RotaTeq can be given alongside other routine childhood vaccines, such as diphtheria-tetanus-pertussis (DTaP), inactivated polio (IPV), and Haemophilus influenzae type B (Hib).
- Immune-suppressing medications: Infants who are taking medications that weaken the immune system, such as chemotherapy or corticosteroids, should consult their doctor before receiving RotaTeq.
Alternatives to RotaTeq
- Rotarix: Another rotavirus vaccine that is given as a series of two oral doses and is also used to prevent rotavirus gastroenteritis in infants.
- Oral rehydration therapy: While not a vaccine, oral rehydration therapy is used to treat dehydration caused by diarrhea in infants and young children, which is often a result of rotavirus infection.
