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Rocklatan
Rocklatan (netarsudil and latanoprost) is a combination eye drop medication used for the treatment of ocular hypertension and open-angle glaucoma. It combines two active ingredients: netarsudil, a Rho kinase inhibitor, and latanoprost, a prostaglandin analog. This combination works synergistically to lower intraocular pressure (IOP) in patients with elevated eye pressure.
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Frequently Asked Questions
How quickly does Rocklatan start to work?
Patients may begin to notice a reduction in intraocular pressure within several hours after administration, with maximum effects typically seen after several weeks of consistent use.
Can I use Rocklatan while pregnant or breastfeeding?
Consult your healthcare provider before using Rocklatan if you are pregnant, planning to become pregnant, or breastfeeding to assess any potential risks.
Are there any specific dietary restrictions while using Rocklatan?
There are no specific dietary restrictions associated with the use of Rocklatan.
What should I do if I miss a dose of Rocklatan?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Rocklatan safe for long-term use?
Rocklatan is intended for long-term management of ocular hypertension and glaucoma. Regular follow-ups with an eye care provider are important to monitor effectiveness and any potential side effects.
Comprehensive Drug Guide
How Does Rocklatan Work?
- Reducing aqueous humor production and increasing outflow:
- Netarsudil enhances the outflow of aqueous humor through the trabecular meshwork by inhibiting Rho kinase, which helps improve drainage and lower IOP.
- Latanoprost increases the uveoscleral outflow of aqueous humor, further contributing to reduced eye pressure.
Common Dosages
- Ophthalmic solution: Usually provided as 0.02% netarsudil and 0.005% latanoprost.
Typical Dosing
- The usual recommended dosing is one drop in the affected eye(s) once daily, preferably in the evening.
Typical Dosing
FDA Approved Indications
- Lowering intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Who Shouldn't Take Rocklatan?
- Known hypersensitivity to netarsudil, latanoprost, or any components of the formulation.
- Active ocular infection or inflammation.
Advice From The Pharmacist
- Instruct patients on the correct technique for administering eye drops, including how to avoid touching the dropper tip to prevent contamination.
- Advise patients to remove contact lenses before applying Rocklatan and wait at least 15 minutes before reinserting them.
- Discuss potential side effects, including eye redness, stinging, or discomfort, and encourage patients to report any severe or unusual symptoms.
Side Effects of Rocklatan
Common Side Effects
- Eye redness or conjunctival hyperemia
- Eye irritation or discomfort
- Stinging or burning sensation upon instillation
- Changes in eyelash pigmentation or growth
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing).
Risks and Warnings of Rocklatan
- Iris Pigmentation Changes: Latanoprost may cause darkening of the iris, which is usually permanent; patients should be informed of this potential side effect.
- Cardiovascular Effects: Patients with a history of cardiovascular disease should be monitored, as prostaglandin analogs can affect heart rate and blood pressure.
Interactions with Rocklatan
Common Drug Interactions
- Other Ocular Medications: Patients should inform their healthcare provider about all eye medications they are using to avoid potential interactions or compounded effects.
Alternatives to Rocklatan
- Other Glaucoma Treatments: Alternatives may include other classes of medications such as beta-blockers, carbonic anhydrase inhibitors, or alpha agonists, depending on the specific needs and response of the patient.
