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Rhopressa
Rhopressa (netarsudil) is a topical ophthalmic solution indicated for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is specifically designed to lower IOP by targeting multiple mechanisms involved in aqueous humor outflow, thereby helping to prevent vision loss associated with glaucoma.
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Frequently Asked Questions
How quickly does Rhopressa start to work?
Patients may start to see a reduction in intraocular pressure within a few hours of administration, with optimal effects observed over several weeks of consistent use.
Can I stop taking Rhopressa suddenly?
It is important to continue using Rhopressa as prescribed to maintain intraocular pressure control. Consult your healthcare provider before making any changes to your treatment regimen.
Are there any specific dietary restrictions while taking Rhopressa?
There are no specific dietary restrictions associated with Rhopressa.
What should I do if I miss a dose of Rhopressa?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Rhopressa safe for long-term use?
Rhopressa is generally safe for long-term use under medical supervision. Regular follow-ups with your healthcare provider are essential to monitor intraocular pressure and any potential side effects.
Comprehensive Drug Guide
How Does Rhopressa Work?
Netarsudil, the active ingredient in Rhopressa, works by inhibiting the Rho kinase enzyme, which plays a role in regulating the actin cytoskeleton in trabecular meshwork cells. This inhibition enhances aqueous humor outflow through the trabecular meshwork, leading to a reduction in IOP. Additionally, netarsudil may also decrease aqueous humor production.
Common Dosages
- Ophthalmic solution: 0.02% netarsudil.
Typical Dosing
- The usual dosage is one drop in the affected eye(s) once daily, preferably in the evening.
Typical Dosing
FDA Approved Indications
- Reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Who Shouldn't Take Rhopressa?
- Known hypersensitivity to netarsudil or any components of the formulation.
- Active ocular infections or conditions.
Advice From The Pharmacist
- Instruct patients on the proper technique for administering eye drops to ensure effective delivery of the medication to the eye.
- Advise patients to avoid touching the dropper tip to any surface, including the eye, to prevent contamination.
- Encourage regular follow-ups with their healthcare provider to monitor IOP and assess treatment efficacy.
Side Effects of Rhopressa
Common Side Effects
- Conjunctival hyperemia (redness of the eye)
- Eye irritation or discomfort
- Instillation site pain
- Dry eye
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Changes in vision
Risks and Warnings of Rhopressa
- Ocular Effects: Patients should be monitored for any changes in vision or ocular discomfort, especially during the initial weeks of treatment.
- Hypotension: Although Rhopressa primarily targets intraocular pressure, caution is advised in patients with significant systemic hypotension.
Interactions with Rhopressa
Common Drug Interactions
- Other Ophthalmic Medications: When using multiple eye drops, patients should be advised to wait at least 5 minutes between different medications to avoid dilution and ensure effectiveness.
Alternatives to Rhopressa
- Other IOP-Lowering Agents: Such as prostaglandin analogs (e.g., latanoprost) or beta-blockers (e.g., timolol), which may be used alone or in combination for managing glaucoma.
