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Recombivax HB

Recombivax HB is a recombinant hepatitis B vaccine used to prevent infection caused by the hepatitis B virus (HBV). This vaccine is crucial in protecting against hepatitis B, which can lead to chronic liver disease, cirrhosis, and liver cancer. Recombivax HB is effective in inducing an immune response to the virus, enabling the body to recognize and fight the infection if exposed.

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Frequently Asked Questions

How effective is Recombivax HB?
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Recombivax HB is highly effective, with studies showing that it produces protective antibody levels in approximately 95% of recipients.

Can I get hepatitis B from the vaccine?
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No, Recombivax HB contains only non-infectious components of the virus and cannot cause hepatitis B infection.

What should I do if I miss a dose of the vaccine?
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If you miss a scheduled dose, contact your healthcare provider to determine the best course of action to complete the vaccination series.

Are there any specific precautions I should take after receiving the vaccine?
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Most individuals can resume normal activities immediately after vaccination, but it is advisable to monitor for any side effects.

Is Recombivax HB safe for pregnant or breastfeeding women?
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Recombivax HB is considered safe for use during pregnancy and breastfeeding. However, it is always best to consult with a healthcare provider before vaccination.

Comprehensive Drug Guide

How Does Recombivax HB Work?

Recombivax HB works by introducing a non-infectious form of the hepatitis B surface antigen (HBsAg) into the body. This stimulates the immune system to produce antibodies against the hepatitis B virus, providing immunity without causing the disease. If exposed to the actual virus in the future, the immune system is primed to mount a rapid and effective response.

What is Recombivax HB Used For?


Typical Dosing

FDA Approved Indications

  • Prevention of hepatitis B virus infection in individuals at risk, including infants, children, and adults.


Who Shouldn't Take Recombivax HB?

  • Known hypersensitivity to any component of the vaccine, including yeast proteins.
  • Severe allergic reaction after a previous dose of the hepatitis B vaccine.


Advice From The Pharmacist

  • Ensure that patients understand the importance of completing the full vaccination series for optimal protection against hepatitis B.
  • Monitor for any allergic reactions post-vaccination, especially if there is a history of allergies.
  • Encourage patients to maintain regular follow-ups to check for antibody levels, especially in high-risk individuals.


Side Effects of Recombivax HB

Common Side Effects

  • Pain or swelling at the injection site
  • Fatigue
  • Mild fever
  • Headache
  • Nausea


Uncommon/Severe Side Effects

  • Severe allergic reactions (such as rash, itching, or difficulty breathing)
  • Guillain-Barré syndrome (very rare)


Risks and Warnings of Recombivax HB

  • Allergic Reactions: Patients with a history of allergies should be monitored closely after vaccination.
  • Immunocompromised Individuals: While the vaccine is safe for immunocompromised patients, it may not be as effective in producing a sufficient immune response.


Interactions with Recombivax HB

Common Drug Interactions

  • Immunosuppressive Therapy: Patients undergoing immunosuppressive treatment may have a diminished response to the vaccine; consult with a healthcare provider regarding vaccination timing.


Alternatives to Recombivax HB

  • Other Hepatitis B Vaccines: Other brands of hepatitis B vaccines may be considered for similar indications.
  • Post-Exposure Prophylaxis: In cases of potential exposure to HBV, passive immunization with hepatitis B immune globulin (HBIG) may be indicated alongside vaccination.