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Reclipsen
Reclipsen (generic name: ethinyl estradiol and desogestrel) is a combination oral contraceptive used to prevent pregnancy. It contains two hormones: ethinyl estradiol (a synthetic estrogen) and desogestrel (a progestin), which work together to prevent ovulation (the release of an egg from the ovary). Reclipsen also thickens the cervical mucus, making it harder for sperm to reach the egg, and alters the uterine lining, reducing the likelihood of implantation. When taken correctly, Reclipsen is highly effective at preventing pregnancy.
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Frequently Asked Questions
How effective is Reclipsen at preventing pregnancy?
When taken correctly, Reclipsen is over 99% effective at preventing pregnancy. However, missing doses or taking the pill inconsistently can reduce its effectiveness.
Can Reclipsen cause weight gain?
Weight gain is a possible side effect of Reclipsen, although it is generally mild. Hormonal changes may cause fluid retention in some users.
What should I do if I miss a pill?
If you miss one pill, take it as soon as you remember, even if it means taking two pills in one day. If you miss two or more pills, follow the specific instructions provided in the package insert and use a backup form of contraception, such as condoms, until you have taken active pills for 7 consecutive days.
Does Reclipsen protect against sexually transmitted infections (STIs)?
No, Reclipsen does not provide protection against STIs. Use condoms to protect against sexually transmitted infections.
Can I use Reclipsen if I am breastfeeding?
It is generally recommended to avoid combination oral contraceptives while breastfeeding, as they can reduce milk production. Progestin-only contraceptives or non-hormonal methods are typically preferred during this time.
Comprehensive Drug Guide
How Does Reclipsen Work?
Reclipsen works by suppressing ovulation and altering the cervical mucus and uterine lining. The synthetic estrogen and progestin in the pill inhibit the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are necessary for ovulation. In addition, the thickened cervical mucus makes it more difficult for sperm to reach the egg, and the thinning of the uterine lining reduces the chances of implantation.
Common Dosages
- 0.15 mg desogestrel / 0.03 mg ethinyl estradiol tablets, taken once daily for 21 days, followed by 7 placebo tablets for the remaining week.
Typical Dosing
- Take one active tablet daily for 21 days, followed by one inert tablet daily for 7 days.
- Start a new pack after completing the 28-day cycle (21 active and 7 placebo tablets).
- It is important to take Reclipsen at the same time every day to ensure maximum effectiveness.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women who choose oral contraception as their birth control method.
Who Shouldn't Take Reclipsen?
- History of blood clots, deep vein thrombosis (DVT), or pulmonary embolism
- History of stroke or heart attack
- Uncontrolled high blood pressure
- Known or suspected breast cancer or other hormone-sensitive cancers
- Liver disease
- Women over 35 years of age who smoke, as this increases the risk of cardiovascular events
Advice From The Pharmacist
- Take Reclipsen at the same time every day, preferably with food, to reduce the risk of nausea and ensure maximum effectiveness.
- If you miss a dose, take it as soon as you remember. If you miss two or more pills, follow the specific instructions provided in the package insert and use backup contraception (such as condoms) until you have taken active pills for 7 consecutive days.
- Reclipsen does not protect against sexually transmitted infections (STIs). Use condoms to protect against STIs.
- Some medications, such as antibiotics or anticonvulsants, can decrease the effectiveness of Reclipsen. Inform your healthcare provider of any other medications you are taking.
- If you experience severe headaches, chest pain, or sudden shortness of breath, contact your healthcare provider immediately, as these could be signs of a serious side effect, such as a blood clot.
Side Effects of Reclipsen
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Weight gain
- Mood changes
- Breakthrough bleeding or spotting, especially during the first few months of use
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke or heart attack
- Severe allergic reactions, including swelling or difficulty breathing
- Liver problems, including liver tumors
Risks and Warnings of Reclipsen
- Blood Clot Risk: Women taking Reclipsen may have an increased risk of developing blood clots, especially if they smoke, are overweight, or have a family history of clotting disorders. Women over 35 who smoke should avoid using Reclipsen due to the high risk of cardiovascular events.
- Breast Cancer: There is a small but increased risk of breast cancer in women who use combination oral contraceptives, particularly in those with a family history of breast cancer.
- Hypertension: Reclipsen can raise blood pressure in some women. Regular monitoring of blood pressure is recommended.
- Liver Disease: Women with pre-existing liver disease should avoid Reclipsen, as it can exacerbate liver problems.
Interactions with Reclipsen
Common Drug Interactions
- Antibiotics: Certain antibiotics, such as rifampin, may reduce the effectiveness of Reclipsen. Use a backup method of contraception if taking these medications.
- Anticonvulsants: Medications like phenytoin and carbamazepine may decrease the effectiveness of Reclipsen.
- St. John's Wort: This herbal supplement can reduce the efficacy of Reclipsen, increasing the risk of pregnancy.
Alternatives to Reclipsen
- Loestrin (norethindrone/ethinyl estradiol): Another combination oral contraceptive with lower doses of estrogen.
- Ortho Tri-Cyclen (norgestimate/ethinyl estradiol): A triphasic oral contraceptive with varying hormone levels throughout the cycle.
- NuvaRing (etonogestrel/ethinyl estradiol vaginal ring): A monthly vaginal ring that delivers a continuous low dose of hormones.
- Mirena (levonorgestrel IUD): A long-acting intrauterine device that provides contraception for up to 5 years.
