You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Raloxifene HCl
Raloxifene HCl is a selective estrogen receptor modulator (SERM) used primarily to treat and prevent osteoporosis in postmenopausal women. It is also approved for reducing the risk of invasive breast cancer in women with osteoporosis or those at high risk of developing breast cancer. Raloxifene mimics the effects of estrogen on bones by increasing bone density, while simultaneously blocking estrogen’s effects on breast and uterine tissues, which helps reduce the risk of cancer.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Raloxifene HCl ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Raloxifene to improve bone density?
Raloxifene may take several months to a year to show improvements in bone density. Continued use is often necessary to maintain its benefits.
Can Raloxifene be used for breast cancer treatment?
No, raloxifene is not used to treat active breast cancer. It is only used to reduce the risk of invasive breast cancer in women who are postmenopausal and at high risk.
Can Raloxifene cause hot flashes?
Yes, hot flashes are a common side effect of raloxifene, especially in the early stages of treatment.
Should I take calcium and vitamin D with Raloxifene?
Yes, it is recommended to maintain adequate calcium and vitamin D intake to support bone health while taking raloxifene.
What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.
Comprehensive Drug Guide
How Does Raloxifene HCl Work?
Raloxifene acts by selectively binding to estrogen receptors in different tissues. In bone tissue, it mimics the effect of estrogen, helping to prevent bone loss and increase bone density. In breast and uterine tissues, it acts as an estrogen antagonist, reducing the risk of breast cancer by blocking the stimulating effects of estrogen on these tissues.
Common Dosages
- 60 mg tablets
Typical Dosing
- The typical dose for both the prevention of osteoporosis and the reduction of breast cancer risk is 60 mg once daily, taken with or without food.
Typical Dosing
FDA Approved Indications
- Prevention and treatment of osteoporosis in postmenopausal women
- Reduction of invasive breast cancer risk in postmenopausal women with osteoporosis or those at high risk of breast cancer
Who Shouldn't Take Raloxifene HCl?
- Active or past history of venous thromboembolism (deep vein thrombosis, pulmonary embolism)
- Known hypersensitivity to raloxifene or its components
- Pregnancy or women who could become pregnant, as it may cause harm to the fetus
Advice From The Pharmacist
- Take Raloxifene exactly as prescribed, usually once daily, and can be taken with or without food.
- Maintain adequate calcium and vitamin D intake while taking this medication to support bone health.
- Be aware of the symptoms of blood clots, such as leg pain, swelling, or sudden shortness of breath, and seek medical attention if they occur.
- Raloxifene is typically prescribed only for postmenopausal women, and it should not be used during pregnancy.
Side Effects of Raloxifene HCl
Common Side Effects
- Hot flashes
- Leg cramps
- Swelling of the hands, feet, or ankles
- Flu-like symptoms
Uncommon/Severe Side Effects
- Increased risk of blood clots (e.g., deep vein thrombosis or pulmonary embolism)
- Stroke
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
Risks and Warnings of Raloxifene HCl
- Risk of Blood Clots: Raloxifene increases the risk of venous thromboembolism (blood clots), including deep vein thrombosis and pulmonary embolism, especially during the first few months of treatment.
- Stroke Risk: In women with a history of heart disease or stroke, raloxifene may increase the risk of fatal stroke.
- Discontinuation Before Surgery: It may be necessary to stop raloxifene at least 72 hours before surgery or periods of prolonged immobility, as these increase the risk of blood clots.
Interactions with Raloxifene HCl
Common Drug Interactions
- Estrogen supplements: Should not be taken together with raloxifene as they may counteract each other’s effects.
- Cholestyramine: May reduce the absorption and effectiveness of raloxifene.
- Anticoagulants: The combination may increase the risk of bleeding, so monitoring may be required.
Alternatives to Raloxifene HCl
- Alendronate (Fosamax®): A bisphosphonate used to treat osteoporosis by slowing bone loss and increasing bone density.
- Denosumab (Prolia®): A monoclonal antibody used to treat osteoporosis by inhibiting the development of bone-resorbing cells.
- Tamoxifen: Another selective estrogen receptor modulator (SERM) used for breast cancer prevention but with a slightly different risk profile.
