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Prolate
Prolate (active ingredient: levonorgestrel) is a hormonal contraceptive used primarily for the prevention of pregnancy. It is a progestin, which works by inhibiting ovulation, thickening cervical mucus to prevent sperm from reaching an egg, and altering the uterine lining to prevent implantation should fertilization occur. Prolate is also utilized for emergency contraception when taken within a specific time frame after unprotected intercourse.
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Frequently Asked Questions
How effective is Prolate as a contraceptive?
When taken correctly, Prolate can be highly effective in preventing pregnancy, with typical use having an effectiveness rate of about 91%.
Can I use Prolate while breastfeeding?
Levonorgestrel is generally considered safe for breastfeeding mothers, but it’s important to consult with a healthcare provider for personalized advice.
What should I do if I miss a dose of Prolate?
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.
Can I use Prolate as emergency contraception?
Yes, Prolate can be used as emergency contraception. It is most effective when taken within 72 hours after unprotected intercourse.
Are there any serious side effects I should be aware of?
While serious side effects are rare, watch for signs of severe allergic reactions or blood clots, such as swelling, chest pain, or difficulty breathing, and seek medical attention immediately if these occur.
Comprehensive Drug Guide
How Does Prolate Work?
Prolate functions primarily by suppressing ovulation through the inhibition of luteinizing hormone (LH) surge. By doing so, it prevents the ovaries from releasing eggs. Additionally, it thickens the cervical mucus, making it difficult for sperm to enter the uterus, and alters the endometrium, which reduces the likelihood of implantation of a fertilized egg.
Common Dosages
- Tablets: 0.75 mg (single dose) for emergency contraception, or 1.5 mg (as a single dose or in divided doses for regular contraceptive use).
Typical Dosing
- For regular contraceptive use: The recommended dose is typically one tablet taken at the same time each day.
- For emergency contraception: Two tablets of 0.75 mg each taken within 72 hours after unprotected intercourse, preferably as soon as possible.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women of reproductive age
- Emergency contraception (when taken within 72 hours after unprotected intercourse)
Who Shouldn't Take Prolate?
- Known hypersensitivity to levonorgestrel or any of its components
- Current or history of blood clots (thrombosis or thromboembolic disorders)
- Uncontrolled hypertension
- Liver disease
- Certain types of cancer (such as breast cancer)
Advice From The Pharmacist
- Take Prolate exactly as prescribed, and do not skip doses to ensure effective contraception.
- If using as emergency contraception, take it as soon as possible after unprotected intercourse for optimal effectiveness.
- Inform your healthcare provider about all medications and supplements you are taking, as drug interactions can occur.
Side Effects of Prolate
Common Side Effects
- Nausea or vomiting
- Breast tenderness
- Headache
- Fatigue
- Changes in menstrual bleeding patterns (irregular periods)
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Signs of a blood clot (such as leg swelling, chest pain, or difficulty breathing)
Risks and Warnings of Prolate
- Cardiovascular Risk: Women with a history of cardiovascular disease should be monitored closely while on hormonal contraceptives.
- Effectiveness: Prolate is less effective in women who are overweight or obese; consult with a healthcare provider for appropriate alternatives if needed.
- Cautions: Consider potential interactions with other medications, especially those that affect liver enzymes, which can impact the efficacy of hormonal contraceptives
Interactions with Prolate
Common Drug Interactions
- Anticonvulsants: Certain medications used for epilepsy may reduce the effectiveness of Prolate.
- Antibiotics: Some antibiotics may affect the metabolism of hormonal contraceptives; however, the interaction is less significant with most modern antibiotics.
- Other Hormonal Contraceptives: Concurrent use with other hormonal contraceptives should be avoided unless under medical supervision.
Alternatives to Prolate
- Other hormonal contraceptives: Such as combined oral contraceptives (COCs), patches, or hormonal IUDs for ongoing birth control.
- Non-hormonal methods: Such as copper IUDs, condoms, or diaphragms for individuals who prefer non-hormonal options.
