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Probinate

Probinate is a medication used to treat conditions like hypertension (high blood pressure), angina (chest pain), and heart rhythm disorders. It's also used in the management of heart conditions after a heart attack.

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Comprehensive Drug Guide

How Does Probinate Work?

Probinate is a beta-blocker that reduces the amount of work the heart has to do, slowing the heart rate and decreasing blood pressure.

What is Probinate Used For?

FDA indications: Probinate is used for the treatment of hypertension, angina, and heart rhythm disorders. It's also used to improve survival after a heart attack.Off-label uses: Probinate has also been used off-label to manage symptoms of anxiety and overactive thyroid (thyrotoxicosis).

Common Dosages

Tablets: 10mg, 20mg, 40mg, 80mgOral solution:10mg/5mL

Typical Dosing

FDA Approved Indications

  • Hypertension: 40 to 80mg twice a day.Angina: 40mg three to four times a day.Heart rhythm disorders: 10 to 30mg three to four times a day.After a heart attack: 180 to 240mg divided into 2 or 3 doses.

Off-Label Uses

  • Anxiety: 10 to 40mg three to four times a day.Overactive thyroid: 10 to 40mg three to four times a day.

Who Shouldn't Take Probinate?

  • Have a serious heart condition such as "sick sinus syndrome", "AV block" or heart failure.Have severe liver disease.Have asthma or other breathing disorders.Are pregnant, planning to become pregnant, or are breastfeeding (it's not known whether Probinate harms the baby).Have a history of depression.Are diabetic.

Advice From The Pharmacist

  • You might feel drowsy or dizzy. Don't drive or do anything requiring alertness until you know how this drug affects you.Don't stop taking Probinate suddenly unless your doctor tells you to. It could lead to a serious heart problem.Alcohol can make the dizziness worse, so it's best to avoid drinking while taking this medication.Check your pulse regularly. If it's slower than usual, consult your doctor.Stay on top of your check-ups and follow your doctor's instructions.

Side Effects of Probinate

Common Side Effects

  • You might feel drowsy, dizzy, or tired.You might have trouble sleeping.Your hands and feet might feel cold

Uncommon/Severe Side Effects

  • You might have nausea, vomiting, or diarrhea.You might feel short of breath.You might have chest pain or a slow heart rate.