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ProAir HFA
ProAir HFA (generic name: albuterol sulfate) is a short-acting beta-agonist (SABA) used as a bronchodilator to relieve bronchospasm in patients with asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. It works by relaxing the muscles around the airways, allowing them to open up and make breathing easier. ProAir HFA is used as a rescue inhaler to treat sudden breathing difficulties and to prevent exercise-induced bronchospasm (EIB).
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Frequently Asked Questions
How quickly does ProAir HFA start working?
ProAir HFA starts working within minutes of inhalation, providing quick relief from symptoms such as wheezing and shortness of breath.
Can ProAir HFA be used as a long-term treatment for asthma?
No, ProAir HFA is used for short-term relief of symptoms and prevention of exercise-induced bronchospasm. Long-term asthma control usually requires inhaled corticosteroids or other maintenance medications.
How often can I use ProAir HFA?
ProAir HFA is typically used every 4 to 6 hours as needed for relief of bronchospasm. If you need to use it more frequently, consult your healthcare provider to adjust your treatment plan.
Can children use ProAir HFA?
Yes, ProAir HFA can be used in children 4 years of age and older for the treatment of asthma and bronchospasm. Use under the guidance of a healthcare provider.
What should I do if ProAir HFA doesn’t relieve my symptoms?
If you find that ProAir HFA does not relieve your symptoms or you are needing to use it more frequently, consult your healthcare provider as this may indicate that your asthma or COPD is not well-controlled.
Comprehensive Drug Guide
How Does ProAir HFA Work?
ProAir HFA contains albuterol, which works by stimulating beta-2 adrenergic receptors in the smooth muscles of the airways. This stimulation causes the muscles to relax, resulting in bronchodilation—the widening of the airways—which helps to improve airflow and relieve symptoms such as wheezing, coughing, and shortness of breath.
Common Dosages
- Inhaler: Each actuation (puff) delivers 108 mcg of albuterol sulfate.
Typical Dosing
- For bronchospasm: The usual dose is 2 inhalations every 4 to 6 hours as needed.
- For exercise-induced bronchospasm (EIB): The typical dose is 2 inhalations 15 to 30 minutes before exercise.
Typical Dosing
FDA Approved Indications
- Treatment or prevention of bronchospasm in patients with reversible obstructive airway disease, such as asthma or COPD.
- Prevention of exercise-induced bronchospasm (EIB).
Who Shouldn't Take ProAir HFA?
- Known hypersensitivity to albuterol or any of the inhaler's components.
- Severe allergic reactions to similar medications (e.g., other beta-agonists).
Advice From The Pharmacist
- Shake the inhaler well before each use.
- If you are using ProAir HFA for the first time or after a long period of inactivity, prime the inhaler by releasing four test sprays into the air.
- Rinse your mouth with water after each use to help prevent thrush (a fungal infection in the mouth).
- Keep track of the number of doses used, as the inhaler has a limited number of doses.
Side Effects of ProAir HFA
Common Side Effects
- Nervousness
- Shaking (tremors)
- Headache
- Dizziness
- Increased heart rate (tachycardia)
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
- Chest pain
- High blood pressure
Risks and Warnings of ProAir HFA
- Cardiovascular Effects: ProAir HFA can cause increased heart rate and blood pressure, especially at higher doses. Patients with heart conditions should use it with caution.
- Paradoxical Bronchospasm: Rarely, albuterol can cause worsening bronchospasm. If this occurs, stop using the inhaler and seek medical attention immediately.
- Overuse: Frequent use of ProAir HFA may indicate poorly controlled asthma or COPD. Consult your healthcare provider if you find yourself needing to use it more than prescribed.
Interactions with ProAir HFA
Common Drug Interactions
- Beta-blockers: These medications can reduce the effectiveness of albuterol and may worsen bronchospasm.
- Diuretics: These may increase the risk of low potassium levels (hypokalemia) when used with albuterol.
- MAO inhibitors and tricyclic antidepressants: These can increase the cardiovascular effects of albuterol.
Alternatives to ProAir HFA
- Ventolin HFA: Another albuterol inhaler used for similar conditions.
- Xopenex (levalbuterol): A bronchodilator similar to albuterol but with fewer side effects for some patients.
- Advair (fluticasone/salmeterol): A combination inhaler used for long-term asthma and COPD control.
