You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Prefest
Prefest is a combination hormone replacement therapy (HRT) that contains estradiol and norethindrone acetate. It is primarily used to manage menopausal symptoms such as hot flashes, vaginal dryness, and to prevent osteoporosis in postmenopausal women. The combination of estrogen and progestin helps to alleviate symptoms associated with decreased hormone levels during menopause while also reducing the risk of endometrial hyperplasia caused by unopposed estrogen.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Prefest ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Prefest to start working?
Patients may begin to notice improvements in menopausal symptoms within a few weeks, but full benefits may take several months.
Can I stop taking Prefest suddenly?
It is not advisable to stop taking Prefest abruptly without consulting your healthcare provider, as this may lead to a resurgence of symptoms.
Are there any dietary restrictions while taking Prefest?
There are no specific dietary restrictions, but a balanced diet and healthy lifestyle can enhance overall health and well-being.
What should I do if I miss a dose of Prefest?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Prefest safe for long-term use?
Long-term use of Prefest should be regularly evaluated by a healthcare provider to assess the benefits and risks, particularly concerning cardiovascular health and cancer.
Comprehensive Drug Guide
How Does Prefest Work?
- Estradiol: A form of estrogen that helps to alleviate menopausal symptoms by replenishing estrogen levels in the body.
- Norethindrone acetate: A progestin that works by protecting the endometrium (lining of the uterus) from the effects of estrogen alone, thus reducing the risk of hyperplasia and associated cancer.
Common Dosages
- Tablets: 1 mg of estradiol and 0.5 mg of norethindrone acetate, or 0.5 mg of estradiol and 0.1 mg of norethindrone acetate, depending on the formulation.
Typical Dosing
- The usual dose of Prefest is one tablet taken orally once daily, with or without food. The exact formulation and dosage may vary based on individual health needs and should be prescribed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Treatment of moderate to severe vasomotor symptoms associated with menopause (such as hot flashes)
- Management of vulvar and vaginal atrophy due to menopause
- Prevention of osteoporosis in postmenopausal women at high risk for fractures
Who Shouldn't Take Prefest?
- Known hypersensitivity to estradiol, norethindrone, or any of the components
- History of breast cancer or estrogen-dependent neoplasia
- Undiagnosed abnormal vaginal bleeding
- Active or recent thromboembolic disorders (such as deep vein thrombosis or pulmonary embolism)
Advice From The Pharmacist
- Take Prefest exactly as prescribed, and do not stop taking it without consulting your healthcare provider, as this may lead to a return of menopausal symptoms.
- Regular follow-up appointments are important to monitor for side effects and the effectiveness of the treatment.
- Discuss any other medications you are taking to avoid potential interactions.
Side Effects of Prefest
Common Side Effects
- Nausea or vomiting
- Breast tenderness or pain
- Headache
- Mood changes
- Spotting or breakthrough bleeding
Uncommon/Severe Side Effects
- Increased risk of blood clots (thromboembolism)
- Stroke or heart attack
- Certain cancers (such as breast cancer or endometrial cancer)
Risks and Warnings of Prefest
- Cardiovascular Risk: Estrogen therapy has been associated with an increased risk of thromboembolic events. Evaluate individual risk factors before initiating therapy.
- Breast Cancer Screening: Regular mammograms and breast exams are recommended for women undergoing hormone therapy, as there may be an increased risk of breast cancer.
- Liver Function: Monitor liver function regularly, as hormonal therapies can impact liver enzymes.
Interactions with Prefest
Common Drug Interactions
- Anticoagulants: Concomitant use with anticoagulants (such as warfarin) may increase the risk of bleeding; monitor INR levels closely.
- CYP450 Enzyme Inducers/Inhibitors: Certain medications that affect liver enzymes may alter the metabolism of estradiol and norethindrone.
Alternatives to Prefest
- Other Hormonal Therapies: Such as estrogen-only therapy or other combination therapies based on individual needs.
- Non-hormonal Treatments: For managing menopausal symptoms, such as SSRIs, SNRIs, or lifestyle modifications.
