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Portia-28

Portia-28 is an oral contraceptive that contains a combination of ethinyl estradiol and norgestimate, which are hormones that help prevent ovulation. It is primarily used for the prevention of pregnancy but also has benefits in regulating menstrual cycles, reducing menstrual cramps, and treating symptoms of polycystic ovary syndrome (PCOS).



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Frequently Asked Questions

How quickly does Portia-28 start to work?
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If taken correctly, Portia-28 is effective at preventing pregnancy within 7 days. It is advised to use backup contraception during this initial period.

Can I stop taking Portia-28 suddenly?
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It is generally safe to stop taking Portia-28 at any time, but consult your healthcare provider for guidance on managing your contraceptive needs afterward.

Are there any specific dietary restrictions while taking Portia-28?
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There are no specific dietary restrictions associated with Portia-28.

What should I do if I miss a dose of Portia-28?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Follow the specific instructions provided in the patient information leaflet regarding missed doses.

Is Portia-28 safe for long-term use?
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Portia-28 can be used long-term under medical supervision. Regular follow-ups are important to assess overall health and manage any potential side effects.

Comprehensive Drug Guide

How Does Portia-28 Work?

  • Inhibiting ovulation (preventing the release of an egg from the ovary).
  • Thickening the cervical mucus, making it more difficult for sperm to enter the uterus.
  • Altering the endometrial lining, making it less suitable for implantation.


Common Dosages

  • Tablets: Each tablet contains 0.035 mg of ethinyl estradiol and 0.180 mg of norgestimate.

Typical Dosing

  • The usual dosing regimen is to take one tablet orally at the same time every day, starting on the first Sunday after the onset of menstruation or as directed by a healthcare provider. The regimen typically involves taking 21 active tablets followed by 7 placebo tablets.


Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy.
  • Regulation of menstrual cycles and reduction of menstrual-related symptoms.


Who Shouldn't Take Portia-28?

  • Known hypersensitivity to any components of the formulation.
  • History of thromboembolic disorders (such as deep vein thrombosis or pulmonary embolism).
  • Uncontrolled hypertension, certain cancers (e.g., breast cancer), or liver disease.

Advice From The Pharmacist

  • Instruct patients to take Portia-28 exactly as prescribed and to not skip doses to maintain contraceptive effectiveness.
  • Advise patients about the importance of using backup contraception if a dose is missed or taken late.
  • Discuss potential side effects and encourage patients to report any severe reactions or unusual symptoms.

Side Effects of Portia-28

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headaches
  • Mood changes
  • Weight gain

Uncommon/Severe Side Effects

  • Blood clots (deep vein thrombosis or pulmonary embolism)
  • Stroke or heart attack, particularly in smokers over 35 years old
  • Severe allergic reactions (such as rash, itching, or difficulty breathing)

Risks and Warnings of Portia-28

  • Cardiovascular Risks: Patients should be aware of the increased risk of cardiovascular events, especially those with pre-existing conditions or risk factors.
  • Monitor for Signs: Patients should be informed about the signs and symptoms of potential serious side effects, such as leg swelling, severe headache, or vision changes, and advised to seek immediate medical attention if these occur.

Interactions with Portia-28

Common Drug Interactions

  • Other Medications: Certain medications, including some antibiotics, anticonvulsants, and herbal supplements (such as St. John's Wort), may decrease the effectiveness of Portia-28. Patients should discuss all medications they are taking with their healthcare provider.

Alternatives to Portia-28

  • Other Birth Control Methods: Other forms of hormonal contraception, such as the patch, ring, or injectable contraceptives, as well as non-hormonal methods (such as condoms or IUDs), may be considered based on patient preference and medical history.