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Polycin
Polycin is a topical antibiotic ointment that combines polymyxin B and neomycin. It is primarily used for the treatment of superficial bacterial infections of the skin, including infections associated with minor cuts, scrapes, and burns. Polycin works by preventing the growth of bacteria and promoting healing in the affected area.
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Frequently Asked Questions
How quickly does Polycin start to work?
Patients may start to notice improvement in symptoms within a few days of starting treatment, but it's important to complete the full course as prescribed.
Can I stop using Polycin suddenly?
It is generally safe to stop using Polycin when symptoms improve, but complete the full course as directed by your healthcare provider to ensure the infection is fully treated.
Are there any specific dietary restrictions while using Polycin?
There are no specific dietary restrictions associated with the use of Polycin.
What should I do if I miss a dose of Polycin?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Polycin safe for long-term use?
Polycin is intended for short-term use to manage superficial bacterial infections. Long-term use should be monitored by a healthcare provider to assess effectiveness and potential side effects. Regular follow-ups are important to ensure the resolution of the infection.
Comprehensive Drug Guide
How Does Polycin Work?
- Polymyxin B disrupts the bacterial cell membrane, leading to cell death. It is effective against many Gram-negative bacteria.
- Neomycin inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing bacterial growth. It is effective against various Gram-negative and some Gram-positive bacteria.
Common Dosages
- Topical ointment: Usually contains polymyxin B (5000 units) and neomycin (3.5 mg) per gram.
Typical Dosing
- The usual recommended dosing is to apply a thin layer of the ointment to the affected area 1 to 3 times daily, depending on the severity of the infection and as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Topical treatment of superficial bacterial infections of the skin.
Who Shouldn't Take Polycin?
- Known hypersensitivity to polymyxin B, neomycin, or any components of the formulation.
- Widespread or deep puncture wounds, animal bites, or serious burns.
Advice From The Pharmacist
- Instruct patients to clean the affected area thoroughly before applying the ointment.
- Advise patients to use Polycin as directed and to avoid using it for longer than recommended to minimize the risk of developing antibiotic resistance.
- Discuss potential side effects, such as local irritation or allergic reactions, and encourage patients to report any severe or unusual symptoms.
Side Effects of Polycin
Common Side Effects
- Local irritation or itching at the application site
- Redness or swelling
- Dryness or peeling of the skin
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Superinfection or resistance if used excessively.
Risks and Warnings of Polycin
- Prolonged Use: Avoid using Polycin for an extended period, as this can lead to the overgrowth of non-susceptible organisms, including fungi.
- Monitoring: Patients should be monitored for signs of secondary infection or worsening of the initial condition.
Interactions with Polycin
Common Drug Interactions
- Other Topical Medications: Patients should inform their healthcare provider about all topical medications they are using to avoid potential interactions or irritation.
Alternatives to Polycin
- Other Topical Antibiotics: Alternatives may include other topical antibiotics like bacitracin or mupirocin, depending on the type and severity of the infection.
