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Pheyo

Pheyo (phenylephrine hydrochloride) is a sympathomimetic agent used primarily as a decongestant in various over-the-counter formulations. It is effective in relieving nasal congestion associated with conditions such as the common cold, allergies, and sinusitis. Pheyo works by constricting blood vessels in the nasal passages, leading to reduced swelling and increased airflow.



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Frequently Asked Questions

How quickly does Pheyo start to work?
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Phenylephrine typically begins to relieve nasal congestion within 30 minutes of administration, with peak effects occurring within a few hours.

Can I stop taking Pheyo suddenly?
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It is generally safe to stop taking Pheyo at any time; however, consult your healthcare provider if you have been using it regularly for an extended period.

Are there any specific dietary restrictions while using Pheyo?
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There are no specific dietary restrictions associated with Pheyo, but patients should monitor their sodium intake if they have hypertension.

What should I do if I miss a dose of Pheyo?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is Pheyo safe for long-term use?
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Pheyo is intended for short-term relief of nasal congestion. Long-term use should be monitored by a healthcare provider to avoid potential side effects and complications related to prolonged vasoconstriction.

Comprehensive Drug Guide

How Does Pheyo Work?

Phenylephrine works primarily as an alpha-1 adrenergic receptor agonist. When administered, it stimulates these receptors in the smooth muscle of blood vessels, leading to vasoconstriction. This action reduces blood flow to the nasal mucosa, resulting in decreased swelling and congestion.



Common Dosages

  • Oral tablets: Common strengths include 10 mg and 20 mg.
  • Nasal sprays: Available in concentrations of 0.25% to 1%.

Typical Dosing

  • For adults and children over 12 years of age, the typical oral dose is 10 mg to 20 mg every 4 hours as needed, not exceeding 60 mg per day.
  • For nasal spray, the usual dosing is 1 to 2 sprays in each nostril every 4 hours, but not more than 3 doses in 24 hours.


Typical Dosing

FDA Approved Indications

  • Relief of nasal congestion due to the common cold, hay fever, and other upper respiratory allergies.


Pediatric Dosing


Who Shouldn't Take Pheyo?

  • Known hypersensitivity to phenylephrine or any components of the formulation.
  • Severe hypertension or severe coronary artery disease.


Advice From The Pharmacist

  • Instruct patients to use Pheyo as directed and to avoid exceeding the recommended dosage to minimize the risk of side effects.
  • Advise patients to consult with a healthcare provider if symptoms persist for more than a few days or worsen.
  • Discuss potential side effects, including increased blood pressure, headache, and insomnia, and encourage patients to report any severe or concerning symptoms.


Side Effects of Pheyo

Common Side Effects

  • Elevated blood pressure
  • Headache
  • Dizziness
  • Insomnia
  • Nervousness


Uncommon/Severe Side Effects

  • Severe allergic reactions (such as rash, itching, or difficulty breathing)
  • Reflex bradycardia (slow heart rate) in some patients.


Risks and Warnings of Pheyo

  • Cardiovascular Concerns: Caution is advised in patients with a history of hypertension, heart disease, or stroke, as phenylephrine can increase blood pressure.
  • Monitoring: Patients should be monitored for any signs of cardiovascular events, especially if they have underlying conditions.


Interactions with Pheyo

Common Drug Interactions

  • Other Medications: Patients should inform their healthcare provider about all medications they are taking, particularly other decongestants, blood pressure medications, and antidepressants, as these can interact with phenylephrine and affect blood pressure.


Alternatives to Pheyo

Other Decongestants: Alternatives may include pseudoephedrine or oxymetazoline, depending on the patient's needs and any contraindications.