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Pheoxia
Pheoxia (phenylephrine) is a sympathomimetic decongestant used primarily to relieve nasal congestion due to colds, allergies, and sinusitis. It works by constricting blood vessels in the nasal passages, leading to reduced swelling and improved airflow. Pheoxia is available in various formulations, including oral tablets, nasal sprays, and liquid forms.
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Frequently Asked Questions
How quickly does Pheoxia start to work?
Phenylephrine typically begins to relieve nasal congestion within 30 minutes of administration, with peak effects usually occurring within a few hours.
Can I stop taking Pheoxia suddenly?
It is generally safe to stop taking Pheoxia at any time; however, consult your healthcare provider if you have been using it regularly for an extended period.
Are there any specific dietary restrictions while using Pheoxia?
There are no specific dietary restrictions associated with the use of Pheoxia, but patients should monitor their sodium intake if they have hypertension.
What should I do if I miss a dose of Pheoxia?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Pheoxia safe for long-term use?
Pheoxia is intended for short-term relief of nasal congestion. Long-term use should be monitored by a healthcare provider to avoid potential side effects and complications related to prolonged vasoconstriction. Regular follow-ups are important to ensure the resolution of the underlying condition.
Comprehensive Drug Guide
How Does Pheoxia Work?
Pheoxia works primarily as an alpha-1 adrenergic receptor agonist. When administered, it stimulates these receptors in the smooth muscle of blood vessels, resulting in vasoconstriction. This action leads to decreased blood flow to the nasal mucosa, reducing swelling and congestion.
Common Dosages
- Oral tablets: Common strengths include 10 mg and 20 mg.
- Nasal sprays: Available in concentrations of 0.25% to 1%.
Typical Dosing
- For adults and children over 12 years of age, the typical oral dose is 10 mg to 20 mg every 4 hours as needed, not exceeding 60 mg per day.
- For nasal spray, the usual dosing is 1 to 2 sprays in each nostril every 4 hours, but not more than 3 doses in 24 hours.
Typical Dosing
FDA Approved Indications
- Relief of nasal congestion due to colds, allergies, and sinusitis.
Who Shouldn't Take Pheoxia?
- Known hypersensitivity to phenylephrine or any components of the formulation.
- Severe hypertension or severe coronary artery disease.
Advice From The Pharmacist
- Instruct patients to use Pheoxia as directed and to avoid exceeding the recommended dosage to minimize the risk of side effects.
- Advise patients to consult with a healthcare provider if symptoms persist for more than a few days or worsen.
- Discuss potential side effects, including increased blood pressure, headache, and insomnia, and encourage patients to report any severe or concerning symptoms.
Side Effects of Pheoxia
Common Side Effects
- Elevated blood pressure
- Headache
- Dizziness
- Insomnia
- Nervousness
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Reflex bradycardia (slow heart rate) in some patients.
Risks and Warnings of Pheoxia
- Cardiovascular Concerns: Caution is advised in patients with a history of hypertension, heart disease, or stroke, as phenylephrine can increase blood pressure.
- Monitoring: Patients should be monitored for any signs of cardiovascular events, especially if they have underlying conditions.
Interactions with Pheoxia
Common Drug Interactions
- Other Medications: Patients should inform their healthcare provider about all medications they are taking, including other decongestants, blood pressure medications, and antidepressants, as these can interact with phenylephrine and affect blood pressure.
Alternatives to Pheoxia
- Other Decongestants: Alternatives may include pseudoephedrine or oxymetazoline, depending on the patient's needs and any contraindications.
