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Phenazo
Phenazo (generic name: phenazopyridine) is a urinary tract analgesic used to relieve pain, burning, urgency, and discomfort associated with urinary tract infections (UTIs) or other urinary conditions that cause irritation of the bladder and urethra. Phenazopyridine works by providing a soothing effect on the lining of the urinary tract but does not treat the underlying infection. It is typically used alongside antibiotics for short-term relief of UTI symptoms.
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Frequently Asked Questions
How long does it take for Phenazo to relieve symptoms?
Relief from urinary pain and discomfort typically occurs within 1 hour of taking Phenazo.
Can Phenazo cure a UTI?
No, Phenazo only provides symptomatic relief of pain and discomfort. It does not treat the underlying bacterial infection, so it must be used in combination with an antibiotic.
Can I take Phenazo for more than two days?
Phenazo should not be used for more than two days unless directed by a healthcare provider. Continued use may mask symptoms of a more serious underlying condition.
Will Phenazo change the color of my urine?
Yes, Phenazo commonly causes reddish-orange discoloration of urine, which is harmless but can stain clothing or other items.
Will Phenazo change the color of my urine?
Yes, Phenazo commonly causes reddish-orange discoloration of urine, which is harmless but can stain clothing or other items.
Can I take Phenazo with other UTI medications?
Yes, Phenazo can be taken with antibiotics prescribed for a UTI. However, always consult with a healthcare provider before combining medications.
Comprehensive Drug Guide
How Does Phenazo Work?
Phenazopyridine provides relief by exerting a local analgesic effect on the mucosa of the urinary tract. It temporarily soothes irritation, reducing the burning sensation and discomfort caused by inflammation in the bladder or urethra. However, it does not treat the bacterial cause of urinary infections.
Common Dosages
- OTC tablets: 95 mg or 97.5 mg
- Prescription tablets: 200 mg
Typical Dosing
- For adults, the typical dose is 200 mg three times daily after meals for up to two days, in combination with an antibiotic for urinary tract infections.
- For OTC formulations, follow the label directions, typically 95 mg taken three times a day after meals.
Typical Dosing
FDA Approved Indications
- Symptomatic relief of discomfort, pain, burning, and urgency associated with urinary tract infections or other irritative urinary conditions.
Who Shouldn't Take Phenazo?
- Known hypersensitivity to phenazopyridine or any component of the formulation
- Severe kidney disease or liver disease
- G6PD deficiency, a genetic disorder that affects red blood cells
Advice From The Pharmacist
- Take Phenazo after meals to minimize stomach upset.
- Do not use for more than two days unless directed by a healthcare provider. This medication is intended for short-term relief while the underlying infection is treated with antibiotics.
- Phenazo may turn urine a reddish-orange color, which is harmless but can stain clothing or contact lenses.
- If you experience symptoms of jaundice (yellowing of the skin or eyes), discontinue use and consult a healthcare provider immediately.
- Stay well-hydrated while taking Phenazo to support urinary health.
Side Effects of Phenazo
Common Side Effects
- Discoloration of urine (reddish-orange)
- Mild stomach upset or nausea
- Headache
Uncommon/Severe Side Effects
- Yellowing of the skin or eyes (jaundice), indicating liver issues
- Blue or purple skin discoloration (a sign of methemoglobinemia)
- Severe allergic reactions (rash, itching, swelling, difficulty breathing)
Risks and Warnings of Phenazo
- Kidney or Liver Impairment: Phenazo should be used cautiously in patients with kidney or liver disease, as it is metabolized and excreted by these organs.
- Prolonged Use: Do not use Phenazo for more than two days without consulting a healthcare provider, as it does not treat the underlying infection and can mask symptoms of a more serious condition.
- Methemoglobinemia Risk: Rarely, Phenazo can cause methemoglobinemia, a condition where too little oxygen is delivered to the body’s tissues, resulting in blue or purple skin.
Interactions with Phenazo
Common Drug Interactions
- Antibiotics: While there are no direct interactions with antibiotics, Phenazo does not replace antibiotic treatment and is only for symptomatic relief.
- Liver or kidney medications: Use cautiously with other drugs that affect liver or kidney function.
Alternatives to Phenazo
- Azo Standard®: Another over-the-counter urinary analgesic that contains phenazopyridine.
- Uristat®: Another OTC urinary pain reliever with phenazopyridine.
- Cranberry supplements: Sometimes used as a preventive measure for UTIs, though not a direct replacement for Phenazo.
