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Perforomist
Perforomist (formoterol fumarate) is a long-acting beta-agonist (LABA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD). It helps to relax the muscles of the airways, making it easier to breathe and providing prolonged relief from bronchospasm.
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Frequently Asked Questions
How quickly does Perforomist work?
Patients may start to notice improvements in breathing within minutes of administration, with peak effects occurring within 1-3 hours.
Can I use Perforomist with other inhalers?
Yes, but consult your healthcare provider to ensure proper scheduling and avoid excessive use of bronchodilators.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Is Perforomist safe during pregnancy?
Consult your healthcare provider before using Perforomist during pregnancy to evaluate potential risks and benefits.
What are the signs of serious side effects to watch for?
Monitor for symptoms of severe allergic reactions or cardiovascular effects, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Perforomist Work?
Perforomist works by selectively stimulating beta-2 adrenergic receptors in the bronchial smooth muscle. This leads to relaxation of the airway muscles, resulting in bronchodilation and improved airflow in patients with COPD.
Common Dosages
Perforomist is typically available in the following form:
- Inhalation solution: Commonly available in a dosage of 20 mcg per 2 mL vial for use with a nebulizer.
Typical Dosing
- Adults: The usual recommended dose is 20 mcg (1 vial) inhaled via nebulization twice daily.
Typical Dosing
FDA Approved Indications
Maintenance treatment of bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD).
Who Shouldn't Take Perforomist?
- Known hypersensitivity to formoterol or any component of the formulation.
- Acute bronchospasm or conditions requiring immediate bronchodilation.
Advice From The Pharmacist
- Use Perforomist exactly as prescribed and do not exceed the recommended dosage.
- It is intended for maintenance therapy and should not be used as a rescue inhaler for acute asthma or COPD attacks.
- Monitor for any changes in breathing or worsening symptoms, and report these to your healthcare provider.
Side Effects of Perforomist
Common Side Effects
- Tremors
- Nervousness
- Headache
- Palpitations
- Cough
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Increased heart rate or arrhythmias
Risks and Warnings of Perforomist
- Cardiovascular Effects: Use with caution in patients with pre-existing cardiovascular conditions, as LABAs can increase heart rate and blood pressure.
- Paradoxical Bronchospasm: Monitor for paradoxical bronchospasm, which can occur with any bronchodilator.
Interactions with Perforomist
Common Drug Interactions
- Other Bronchodilators: Use caution when combining with other bronchodilators or medications that affect the cardiovascular system.
- Beta-blockers: May reduce the effectiveness of formoterol and should be used with caution.
Alternatives to Perforomist
- Other LABAs: Such as salmeterol for similar indications.
- Inhaled Corticosteroids: For patients with asthma or COPD requiring anti-inflammatory treatment.
