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PEG-KCl-NaCl-NaSulf-Na Asc-C

PEG-KCl-NaCl-NaSulf-Na Asc-C is a combination oral solution that typically includes polyethylene glycol (PEG), potassium chloride (KCl), sodium chloride (NaCl), sodium sulfate (NaSulf), and ascorbic acid (Vitamin C). This formulation is commonly used as a bowel cleansing agent prior to diagnostic procedures such as colonoscopy. It helps to hydrate the colon and facilitate the clearance of fecal matter.



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Frequently Asked Questions

How quickly does the solution work?
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Patients typically begin to experience bowel movements within 1 to 3 hours after taking the solution, depending on individual response.

Can I eat before using this solution?
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Patients are usually advised to follow a clear liquid diet before using the solution. Specific dietary instructions should be provided by the healthcare provider.

What should I do if I experience severe side effects?
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If you experience severe nausea, vomiting, or abdominal pain, contact your healthcare provider immediately.

Is this solution safe during pregnancy?
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Consult your healthcare provider before using this solution during pregnancy to evaluate potential risks and benefits.

What are the signs of electrolyte imbalance to watch for?
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Monitor for symptoms such as muscle cramps, weakness, or changes in heart rate, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does PEG-KCl-NaCl-NaSulf-Na Asc-C Work?

The components of PEG-KCl-NaCl-NaSulf-Na Asc-C work together to promote bowel evacuation:

  • PEG: A non-absorbable osmotic agent that retains water in the intestinal lumen, increasing the volume of stool and promoting peristalsis.
  • KCl and NaCl: Electrolytes that help maintain electrolyte balance during the cleansing process.
  • NaSulf: A saline laxative that contributes to the osmotic effect and enhances fluid secretion into the intestines.
  • Ascorbic Acid (Vitamin C): Acts as an antioxidant and may contribute to the overall bowel cleansing effect.

Common Dosages

The solution is typically available in the following forms:

  • Powder for oral solution: Instructions for reconstitution may vary by product, usually requiring mixing with water.

Typical Dosing

  • Adults: The typical dosing regimen involves taking the solution the evening before and the morning of the procedure, as directed by the healthcare provider. Specific dosing instructions will vary depending on the formulation.

Typical Dosing

FDA Approved Indications

Colonoscopy preparation: To cleanse the colon prior to diagnostic procedures.

Who Shouldn't Take PEG-KCl-NaCl-NaSulf-Na Asc-C?

  • Known hypersensitivity to any component of the formulation
  • Bowel obstruction or perforation
  • Severe inflammatory bowel disease


Advice From The Pharmacist

  • Follow the preparation instructions carefully and ensure proper hydration during the cleansing process.
  • Inform your healthcare provider about any medications you are taking, as some may affect bowel cleansing or hydration status.
  • Report any severe gastrointestinal symptoms, such as persistent vomiting or abdominal pain, to your healthcare provider.


Side Effects of PEG-KCl-NaCl-NaSulf-Na Asc-C

Common Side Effects

  • Nausea
  • Abdominal cramping
  • Diarrhea
  • Bloating


Uncommon/Severe Side Effects

  • Electrolyte imbalances
  • Severe allergic reactions (rash, itching, swelling)


Risks and Warnings of PEG-KCl-NaCl-NaSulf-Na Asc-C

  • Electrolyte Imbalances: Monitor electrolyte levels, especially in patients with renal impairment or other underlying conditions.
  • Dehydration: Ensure adequate fluid intake to prevent dehydration during the cleansing process.

Interactions with PEG-KCl-NaCl-NaSulf-Na Asc-C

Common Drug Interactions

Other Medications: Inform your healthcare provider about all medications you are taking, especially those affecting electrolyte balance or gastrointestinal motility.

Alternatives to PEG-KCl-NaCl-NaSulf-Na Asc-C

Other Bowel Cleansing Agents: Other formulations, such as sodium phosphate solutions or alternative PEG-based products, may be used for similar indications.