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PEG-3350/Electrolytes

PEG-3350/Electrolytes is a combination oral solution used primarily as a bowel cleansing agent before diagnostic procedures, such as colonoscopy. It contains polyethylene glycol (PEG-3350) and electrolytes, which work together to promote hydration and facilitate the clearance of fecal matter from the intestines.



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Frequently Asked Questions

How quickly does the solution work?
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Patients typically begin to experience bowel movements within 1 to 3 hours after taking the solution, but this can vary.

Can I eat before using this solution?
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Patients are generally advised to follow a clear liquid diet prior to using the solution. Specific dietary instructions should be provided by the healthcare provider.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.

Is this solution safe during pregnancy?
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Consult your healthcare provider before using this solution during pregnancy to evaluate potential risks and benefits.

What are the signs of electrolyte imbalance to watch for?
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Be alert for symptoms such as muscle cramps, weakness, or changes in heart rate, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does PEG-3350/Electrolytes Work?

PEG-3350 works by:

  • Retaining water in the intestinal lumen, increasing stool volume and promoting peristalsis.
  • Electrolytes (such as sodium and potassium) help maintain electrolyte balance and hydration during the bowel cleansing process.


Common Dosages

The solution is typically available in the following form:

  • Powder for oral solution: Usually requiring reconstitution with water prior to use.

Typical Dosing

  • Adults: The typical dosing regimen involves consuming the solution the evening before and the morning of the procedure, as directed by the healthcare provider. Specific dosing instructions will depend on the product formulation.

Typical Dosing

FDA Approved Indications

  • Colonoscopy preparation: To cleanse the colon before diagnostic procedures.


Who Shouldn't Take PEG-3350/Electrolytes?

  • Known hypersensitivity to any component of the formulation
  • Bowel obstruction or perforation
  • Severe inflammatory bowel disease


Advice From The Pharmacist

  • Follow the preparation instructions carefully to ensure effective bowel cleansing.
  • Stay well-hydrated during the process to prevent dehydration.
  • Inform your healthcare provider about any medications you are taking, particularly those that might affect electrolyte balance.


Side Effects of PEG-3350/Electrolytes

Common Side Effects

  • Nausea
  • Abdominal cramping
  • Diarrhea
  • Bloating


Uncommon/Severe Side Effects

  • Electrolyte imbalances
  • Severe allergic reactions (rash, itching, swelling)


Risks and Warnings of PEG-3350/Electrolytes

  • Electrolyte Imbalances: Regularly monitor electrolyte levels, especially in patients with kidney issues or other underlying health conditions.
  • Dehydration: Ensure adequate fluid intake to avoid dehydration during the cleansing process.

Interactions with PEG-3350/Electrolytes

Common Drug Interactions

Other Medications: Inform your healthcare provider about all medications you are taking, especially those affecting electrolyte levels or gastrointestinal motility.

Alternatives to PEG-3350/Electrolytes

Other Bowel Cleansing Agents: Other formulations, such as sodium phosphate solutions or alternative PEG-based products, may also be used for bowel preparation.