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Paremyd

Paremyd (hydroxyamphetamine and tropicamide) is a combination ophthalmic solution used primarily for pupil dilation (mydriasis) during eye examinations. It combines hydroxyamphetamine, which stimulates the dilator muscle of the iris, and tropicamide, an anticholinergic agent that inhibits the sphincter muscle, resulting in effective and rapid dilation of the pupil.



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Frequently Asked Questions

How quickly does Paremyd work?
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Paremyd typically starts to take effect within 15 to 30 minutes after administration.

Can I wear contact lenses while using Paremyd?
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It is recommended to remove contact lenses before using Paremyd and wait at least 15 minutes before reinserting them.

What should I do if I miss a dose?
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If you miss a dose, use it as soon as you remember, especially if it’s close to your scheduled examination. Otherwise, follow the instructions provided by your healthcare provider.

Is Paremyd safe during pregnancy?
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Consult your healthcare provider before using Paremyd during pregnancy to evaluate potential risks and benefits.

What are the signs of serious side effects to watch for?
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Monitor for symptoms of allergic reactions or significant eye discomfort, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does Paremyd Work?

  • Hydroxyamphetamine: Works by stimulating the release of norepinephrine, causing contraction of the dilator muscle of the iris, which leads to pupil dilation.
  • Tropicamide: Blocks the action of acetylcholine on the sphincter muscle of the iris, further promoting dilation by preventing the constriction of the pupil.


Common Dosages

  • Ophthalmic solution: Usually in a concentration of 0.3% hydroxyamphetamine and 0.5% tropicamide.

Typical Dosing

  • Adults and Children: The recommended dose is usually 1 drop in the affected eye(s) as needed for dilation, typically 15 to 30 minutes before the examination.


Typical Dosing

FDA Approved Indications

  • Pupil dilation during ophthalmic examinations.


Who Shouldn't Take Paremyd?

  • Known hypersensitivity to hydroxyamphetamine, tropicamide, or any component of the formulation
  • Narrow-angle glaucoma or a history of angle-closure glaucoma


Advice From The Pharmacist

  • Avoid driving or operating heavy machinery until the effects of the medication have worn off, as it may cause blurred vision.
  • Inform your healthcare provider about any other eye medications you are using.
  • Report any unusual side effects, such as prolonged blurred vision or significant eye discomfort.


Side Effects of Paremyd

Common Side Effects

  • Blurred vision
  • Photophobia (sensitivity to light)
  • Eye irritation or discomfort


Uncommon/Severe Side Effects

  • Allergic reactions (rash, itching, swelling)
  • Increased intraocular pressure


Risks and Warnings of Paremyd

  • Eye Pressure: Use with caution in patients with a history of elevated intraocular pressure or glaucoma.
  • Allergic Reactions: Monitor for any signs of allergic reactions and discontinue use if severe symptoms occur.


Interactions with Paremyd

Common Drug Interactions

  • Other Ophthalmic Medications: Consult your healthcare provider before using other eye drops to avoid potential interactions.


Alternatives to Paremyd

  • Other Mydriatics: Such as phenylephrine or other combinations for pupil dilation.
  • Diagnostic Procedures: Alternative methods for examination if dilation is contraindicated.