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Pandel
Pandel (generic name: hydrocortisone probutate) is a topical corticosteroid used to treat inflammation and itching associated with skin conditions such as eczema, dermatitis, psoriasis, and allergic reactions. It works by reducing inflammation, redness, and itching through its anti-inflammatory properties. Pandel is typically prescribed for short-term use on affected areas of the skin and is available in a cream formulation.
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Frequently Asked Questions
How long can I use Pandel?
Pandel is typically prescribed for short-term use. Long-term use should be avoided unless specifically directed by your doctor, as extended use can cause skin thinning and other side effects.
Can I use Pandel on my face?
Pandel should not be applied to the face, groin, or underarms unless directed by your doctor. The skin in these areas is more sensitive and prone to side effects like thinning.
What should I do if I miss a dose of Pandel?
If you miss a dose, apply it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses.
Is Pandel safe for children?
Pandel can be prescribed to children, but extra caution is needed, as children may be more susceptible to side effects like adrenal suppression and growth delay. Always follow your doctor’s instructions closely.
Can I use Pandel for a skin infection?
Pandel should not be used on bacterial, fungal, or viral skin infections unless directed by your healthcare provider, as it may worsen the infection.
Comprehensive Drug Guide
How Does Pandel Work?
Pandel works by reducing inflammation and immune responses in the skin. Hydrocortisone probutate, the active ingredient, acts by inhibiting the release of chemicals in the body that cause inflammation (such as prostaglandins and leukotrienes). This helps alleviate symptoms like redness, swelling, and itching associated with various skin conditions.
Common Dosages
- Apply a thin layer to the affected area(s) once or twice daily.
Typical Dosing
- Apply a thin layer of Pandel cream to the affected skin area(s) once or twice daily, depending on the severity of the condition and your healthcare provider’s instructions.
- Do not use it on the face, groin, or underarms unless directed by a doctor.
Typical Dosing
FDA Approved Indications
- The relief of inflammation and itching associated with corticosteroid-responsive dermatoses, including conditions like eczema, psoriasis, and dermatitis.
Who Shouldn't Take Pandel?
- Known hypersensitivity to hydrocortisone or any other component of the formulation.
- Skin infections: Pandel should not be applied to bacterial, fungal, or viral skin infections unless directed by a doctor.
Advice From The Pharmacist
- Apply Pandel sparingly to the affected area(s) and avoid covering the treated skin with tight dressings or bandages unless directed by your healthcare provider, as this can increase the absorption of the medication and risk of side effects.
- Wash your hands after applying the cream, unless the hands are the area being treated.
- Do not use Pandel for extended periods, especially on large areas of the body, unless advised by your doctor. Long-term use can lead to thinning of the skin or other side effects.
- Avoid using Pandel on the face, groin, or underarms unless specifically instructed by your doctor.
Side Effects of Pandel
Common Side Effects
- Burning, itching, or stinging at the application site
- Dry skin
- Redness
- Irritation
Uncommon/Severe Side Effects
- Skin thinning or atrophy (especially with long-term use)
- Stretch marks (striae)
- Increased hair growth at the application site
- Infection at the treated area
- Adrenal suppression if used on large areas or under occlusive dressings
Risks and Warnings of Pandel
- Adrenal Suppression: Overuse of topical corticosteroids, particularly on large areas of the body or under occlusive dressings, can suppress the body’s ability to produce its own corticosteroids, leading to adrenal insufficiency.
- Skin Atrophy: Prolonged use of Pandel, especially on delicate skin areas, can lead to thinning of the skin (atrophy), making the skin more susceptible to injury or infection.
- Infection Risk: Pandel should not be used on infected skin unless directed by your doctor. The anti-inflammatory properties of corticosteroids can mask signs of infection and allow it to worsen.
- Pediatric Use: Children may be more sensitive to the effects of corticosteroids, including adrenal suppression and growth delay, especially with prolonged use.
Interactions with Pandel
Common Drug Interactions
- Other corticosteroids: Concurrent use of Pandel with other topical or systemic corticosteroids may increase the risk of side effects such as skin thinning or adrenal suppression.
- Occlusive dressings: Using Pandel under occlusive dressings (like bandages or tight clothing) can enhance the absorption of the medication, increasing the risk of systemic side effects.
Alternatives to Pandel
- Hydrocortisone (over-the-counter): A lower-potency corticosteroid available for mild skin conditions like dermatitis or rashes.
- Triamcinolone acetonide: Another topical corticosteroid often prescribed for moderate to severe inflammatory skin conditions.
- Fluocinonide: A higher-potency topical corticosteroid used for more severe skin conditions that are resistant to other treatments.
