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Opium
Opium is a natural narcotic obtained from the dried latex of the opium poppy (Papaver somniferum). It contains several alkaloids, including morphine, codeine, and thebaine, which are used for their analgesic (pain-relieving) and sedative properties. Opium has a long history of use in traditional medicine but is also associated with significant risks of addiction and abuse.
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Frequently Asked Questions
How quickly does opium relieve pain?
Opium and its derivatives typically provide pain relief within 30 minutes to an hour, depending on the formulation and method of administration.
Can I take opium with food?
While it can be taken with or without food, taking it with food may help reduce gastrointestinal side effects like nausea.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Is opium safe during pregnancy?
Opium use during pregnancy poses risks to both the mother and the fetus and should be avoided unless absolutely necessary. Consult your healthcare provider for guidance.
What are the signs of serious side effects to watch for?
Monitor for signs of respiratory depression, severe allergic reactions, or overdose, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Opium Work?
Opium and its alkaloids exert their effects by binding to opioid receptors in the brain and spinal cord, particularly the mu-opioid receptors. This binding results in decreased perception of pain, altered emotional response to pain, and sedation.
Common Dosages
- Opium tincture: Contains 10% opium and is dosed in drops.
- Opioid tablets or injections: Dosages vary widely based on the specific medication and condition being treated.
Typical Dosing
- For pain relief: Dosage is individualized based on the severity of pain, previous opioid use, and patient response.
Typical Dosing
FDA Approved Indications
- Relief of moderate to severe pain.
- Cough suppression (codeine).
- Diarrhea treatment (in certain formulations).
Who Shouldn't Take Opium?
- Known hypersensitivity to opium or its alkaloids.
- Severe respiratory depression.
- Acute or severe asthma.
- Gastrointestinal obstruction.
Advice From The Pharmacist
- Use opium-based medications exactly as prescribed, and be aware of the potential for dependence and addiction.
- Monitor for signs of opioid misuse, including increased tolerance or seeking multiple prescriptions.
- Do not suddenly discontinue use without consulting your healthcare provider, as this may lead to withdrawal symptoms.
Side Effects of Opium
Common Side Effects
- Drowsiness
- Constipation
- Nausea
- Respiratory depression
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Overdose, which can lead to coma or death.
Risks and Warnings of Opium
- Addiction Potential: There is a high risk of developing tolerance, physical dependence, and addiction with prolonged use.
- Respiratory Depression: Monitor closely for respiratory depression, particularly during dose initiation or when increasing the dose.
Interactions with Opium
Common Drug Interactions
- CNS Depressants: Use with caution when combined with other medications that cause sedation, such as benzodiazepines or alcohol.
- Other Opioids: Combining with other opioids can increase the risk of overdose.
Alternatives to Opium
- Non-opioid Analgesics: Such as acetaminophen or NSAIDs for pain management.
- Other Opioids: Such as hydrocodone or oxycodone, which may be preferred for certain patients based on their medical history.
