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Onzdeaxiatar
Onzdeaxiatar is a combination topical treatment used to treat acne vulgaris. It contains tretinoin (0.025%), benzoyl peroxide (5%), clindamycin (1%), and niacinamide. This combination is effective for treating mild to moderate acne by addressing multiple acne-causing factors, such as bacterial overgrowth, clogged pores, and inflammation. Tretinoin promotes cell turnover, benzoyl peroxide acts as an antimicrobial agent, clindamycin is an antibiotic, and niacinamide helps reduce inflammation and improve skin tone.
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Frequently Asked Questions
How long does it take for Onzdeaxiatar to work?
It may take 6 to 8 weeks of consistent use to see noticeable improvements in acne. Full results may take up to 3 months.
Can I use makeup while using Onzdeaxiatar?
Yes, you can use non-comedogenic (won't clog pores) makeup while using Onzdeaxiatar, but ensure your skin is clean before applying the treatment.
Can I stop using Onzdeaxiatar once my acne clears?
Acne treatments like Onzdeaxiatar are often used for maintenance after acne clears. Consult your healthcare provider for a tailored plan to prevent future breakouts.
Should I avoid any specific skincare products while using Onzdeaxiatar?
Avoid harsh exfoliants, astringents, or alcohol-based products, as these can increase irritation. Use a gentle, non-irritating cleanser and moisturizer.
Can Onzdeaxiatar treat severe acne?
Onzdeaxiatar is typically prescribed for mild to moderate acne. For severe acne, consult a healthcare provider for additional treatments, which may include oral medications.
Comprehensive Drug Guide
How Does Onzdeaxiatar Work?
- Tretinoin increases skin cell turnover, preventing clogged pores and promoting the shedding of dead skin cells.
- Benzoyl peroxide acts as an antimicrobial to kill Propionibacterium acnes, a bacterium that contributes to acne formation.
- Clindamycin reduces bacterial growth, targeting acne-causing bacteria and preventing inflammation.
- Niacinamide (Vitamin B3) soothes inflamed skin, reduces redness, and improves the overall appearance of the skin.
Common Dosages
- Topical cream in a 30-gram bottle with a strength of 0.025% tretinoin, 5% benzoyl peroxide, and 1% clindamycin.
Typical Dosing
- Apply a thin layer of Onzdeaxiatar to the affected area once daily, usually at night, or as directed by a healthcare provider.
- Gently wash and pat the skin dry before applying the cream.
Typical Dosing
FDA Approved Indications
- Mild to moderate acne vulgaris
Who Shouldn't Take Onzdeaxiatar?
- Known hypersensitivity or allergy to tretinoin, benzoyl peroxide, clindamycin, or niacinamide.
- Severe skin conditions such as eczema or rosacea, unless specifically recommended by a healthcare provider.
Advice From The Pharmacist
- Onzdeaxiatar can increase your skin's sensitivity to the sun. Use a broad-spectrum sunscreen and avoid prolonged sun exposure while using this medication.
- Avoid using other topical treatments, especially those containing alcohol, astringents, or exfoliants, as they may increase irritation.
- If irritation, dryness, or peeling occurs, reduce the frequency of application and apply a moisturizer to soothe the skin.
- Be patient, as acne treatments can take 6 to 8 weeks to show significant improvement.
- Store at room temperature and keep the bottle tightly closed when not in use.
Side Effects of Onzdeaxiatar
Common Side Effects
- Dryness
- Redness
- Peeling
- Mild burning or stinging at the application site
Uncommon/Severe Side Effects
- Severe allergic reactions (swelling, rash, difficulty breathing)
- Severe skin irritation if used improperly
Risks and Warnings of Onzdeaxiatar
- Photosensitivity: Tretinoin and benzoyl peroxide can cause increased sensitivity to sunlight, making it important to use sunscreen during the day and limit sun exposure.
- Skin Irritation: Some users may experience excessive dryness or peeling, especially during the first few weeks of treatment. Use a moisturizer and consult your healthcare provider if irritation persists.
- Antibiotic Resistance: Overuse of clindamycin can lead to antibiotic resistance, so use the medication exactly as prescribed.
Interactions with Onzdeaxiatar
Common Drug Interactions
- Topical exfoliants (e.g., salicylic acid or alpha hydroxy acids): Can increase skin irritation when used with tretinoin or benzoyl peroxide.
- Oral antibiotics: Using clindamycin with other antibiotics may increase the risk of antibiotic resistance.
- Photosensitizing agents: Combining Onzdeaxiatar with other photosensitizing medications may increase the risk of sunburn or skin damage.
Alternatives to Onzdeaxiatar
- Differin (adapalene): Another topical retinoid used for treating acne.
- Epiduo: A combination of adapalene and benzoyl peroxide for acne treatment.
- Benzaclin: A combination of benzoyl peroxide and clindamycin, without tretinoin.
- Retin-A (tretinoin): A topical retinoid for treating acne and reducing signs of aging.
