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Olmesartan Medoxomil
Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) used primarily to treat hypertension (high blood pressure). By blocking the action of angiotensin II, a substance that causes blood vessels to constrict, olmesartan helps to relax blood vessels, leading to lower blood pressure and reduced workload on the heart.
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Frequently Asked Questions
How quickly does Olmesartan Medoxomil work?
Patients may begin to see a reduction in blood pressure within 1 to 2 weeks of starting treatment.
Can I take Olmesartan Medoxomil with food?
Yes, it can be taken with or without food.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using Olmesartan Medoxomil?
There are no specific dietary restrictions while using Olmesartan Medoxomil, but a heart-healthy diet is recommended.
Is Olmesartan Medoxomil safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Olmesartan Medoxomil during these periods.
Comprehensive Drug Guide
How Does Olmesartan Medoxomil Work?
Olmesartan Medoxomil works by selectively blocking the binding of angiotensin II to its receptor sites, resulting in vasodilation (widening of blood vessels) and decreased secretion of aldosterone, which helps lower blood pressure and reduce fluid retention.
Common Dosages
- Tablets: Common strengths include 5 mg, 20 mg, and 40 mg.
Typical Dosing
- The usual starting dose for adults is 20 mg taken orally once daily, which may be adjusted based on blood pressure response, with a maximum dose typically not exceeding 40 mg per day.
Typical Dosing
FDA Approved Indications
- Hypertension: for the treatment of high blood pressure in adults and children aged 6 years and older.
Who Shouldn't Take Olmesartan Medoxomil?
- Known hypersensitivity to olmesartan or any component of the formulation.
- History of angioedema related to previous ARB treatment.
- Severe renal impairment.
Advice From The Pharmacist
- Take Olmesartan Medoxomil exactly as prescribed, preferably at the same time each day.
- Monitor your blood pressure regularly to assess the effectiveness of treatment.
- Report any signs of allergic reactions, such as rash or swelling, to your healthcare provider.
Side Effects of Olmesartan Medoxomil
Common Side Effects
- Dizziness or lightheadedness
- Fatigue
- Headache
- Nausea
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Low blood pressure (hypotension)
- Kidney problems (elevated creatinine levels).
Risks and Warnings of Olmesartan Medoxomil
- Kidney Function: Regular monitoring of kidney function is recommended, especially in patients with pre-existing renal conditions or those taking other medications affecting the kidneys.
- Pregnancy: Avoid use during pregnancy due to potential harm to the fetus.
Interactions with Olmesartan Medoxomil
Common Drug Interactions
- Other Antihypertensives: Caution is advised when used with other blood pressure-lowering medications, as they may have additive effects.
- NSAIDs: May reduce the effectiveness of diuretics and potentially worsen renal function when combined.
Alternatives to Olmesartan Medoxomil
- Other ARBs: Such as losartan or valsartan for similar indications.
- Other Antihypertensives: Combination therapies that may include calcium channel blockers or diuretics.
