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Ocella

Ocella is a combination oral contraceptive that contains two hormones: ethinyl estradiol (an estrogen) and drospirenone (a progestin). It is used to prevent pregnancy and is also indicated for the treatment of moderate acne in females who are at least 14 years old and wish to use an oral contraceptive for birth control. Ocella works by inhibiting ovulation, altering the uterine lining, and thickening cervical mucus to prevent sperm from reaching an egg.



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Frequently Asked Questions

How effective is Ocella in preventing pregnancy?
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When taken correctly, Ocella is over 99% effective at preventing pregnancy.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Refer to the patient information for specific guidelines on missed doses.

Can I take Ocella if I smoke?
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Smoking increases the risk of serious cardiovascular side effects when using hormonal contraceptives. It is recommended to stop smoking or discuss alternative contraceptive methods with your healthcare provider.

Is it safe to take Ocella during breastfeeding?
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Consult your healthcare provider, as combined hormonal contraceptives may affect milk production. Progestin-only options may be recommended during breastfeeding.

Can Ocella cause weight gain?
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Some users may experience weight changes, but this varies among individuals. Discuss any concerns about weight changes with your healthcare provider.

Comprehensive Drug Guide

How Does Ocella Work?

  • Inhibition of Ovulation: The hormones suppress ovulation by preventing the release of eggs from the ovaries.
  • Changes in Uterine Lining: It alters the endometrial lining, making it less suitable for implantation.
  • Cervical Mucus Thickening: Drospirenone thickens cervical mucus, which helps block sperm entry.


Common Dosages

  • Tablets: Each pack typically contains 28 tablets, including 21 active tablets (containing hormones) and 7 inactive placebo tablets.

Typical Dosing

  • Adults: The usual dose is one tablet taken orally once daily, starting on the first day of the menstrual cycle or as directed by a healthcare provider. It is important to take the tablet at the same time every day for maximum effectiveness.


Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy in females of reproductive age.
  • Treatment of moderate acne in females who also wish to use an oral contraceptive.


Who Shouldn't Take Ocella?

  • Known hypersensitivity to ethinyl estradiol, drospirenone, or any component of the formulation
  • History of blood clots (deep vein thrombosis or pulmonary embolism)
  • Certain cancers (e.g., breast cancer)
  • Uncontrolled hypertension
  • Liver disease or liver tumors


Advice From The Pharmacist

  • Take Ocella exactly as prescribed and do not skip doses to maintain effective contraceptive coverage.
  • If you miss a dose, follow the instructions provided in the patient information leaflet or consult your healthcare provider.
  • Use backup contraception (such as condoms) if you miss a dose or if you experience vomiting or diarrhea shortly after taking a tablet.
  • Regular check-ups with your healthcare provider are important to monitor any potential side effects or complications.


Side Effects of Ocella

Common Side Effects

  • Nausea
  • Headaches
  • Breast tenderness
  • Weight changes
  • Mood swings


Uncommon/Severe Side Effects

  • Blood clots (thrombosis)
  • Severe allergic reactions (rash, itching, swelling)
  • Liver problems (jaundice, abdominal pain)


Risks and Warnings of Ocella

  • Cardiovascular Risks: Estrogen-containing contraceptives can increase the risk of blood clots, particularly in women who smoke, are over 35 years old, or have a history of cardiovascular disease.
  • Monitor for Symptoms: Be vigilant for signs of thrombosis, such as severe leg swelling, chest pain, or sudden shortness of breath, and seek immediate medical attention if they occur.
  • Cancer Risks: Long-term use of combined oral contraceptives may be associated with an increased risk of certain cancers, including breast and cervical cancer.


Interactions with Ocella

Common Drug Interactions

  • Antibiotics: Some antibiotics may reduce the effectiveness of Ocella; consult your healthcare provider for specific recommendations.
  • Anticonvulsants: Certain medications for seizures may decrease the effectiveness of hormonal contraceptives.
  • Other Medications: Always inform your healthcare provider of all medications you are taking to avoid potential interactions.


Alternatives to Ocella

  • Other Oral Contraceptives: Different formulations of combined or progestin-only pills may be considered.
  • Long-Acting Reversible Contraceptives (LARCs): Such as IUDs or implants for more long-term contraceptive solutions.
  • Barrier Methods: Such as condoms or diaphragms for non-hormonal options.