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Nulytely Lemon-Lime
Nulytely Lemon-Lime is an osmotic laxative solution used for bowel cleansing prior to medical procedures, such as colonoscopy or barium enema X-rays. It contains a combination of polyethylene glycol 3350 (PEG 3350), sodium chloride, sodium bicarbonate, and potassium chloride. The solution works by increasing water retention in the bowel, which softens stools and induces bowel movements, effectively clearing the colon. The lemon-lime flavor makes it more palatable for patients who need to take large volumes of the solution before procedures.
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Frequently Asked Questions
How long does it take for Nulytely to start working?
Most patients start experiencing bowel movements within 1 to 2 hours of starting Nulytely.
Can I drink anything else besides Nulytely during the preparation?
Yes, you can drink clear liquids such as water, broth, tea, or clear juice (but avoid red or purple liquids) in between doses to stay hydrated.
How should I store Nulytely once it is mixed?
After reconstituting the powder, store the solution in the refrigerator and use it within 48 hours.
Can I take my regular medications while using Nulytely?
Check with your healthcare provider before taking any regular medications, as some may need to be adjusted to avoid interfering with the preparation or procedure.
What should I do if I can't finish the full dose of Nulytely?
Contact your healthcare provider if you cannot complete the full dosage, as incomplete bowel cleansing may reduce the effectiveness of your procedure.
Comprehensive Drug Guide
How Does Nulytely Lemon-Lime Work?
Nulytely works by retaining water in the intestines due to the action of polyethylene glycol (PEG 3350). The high-water content softens the stool and stimulates the bowels, leading to frequent and complete evacuation of the contents of the colon. The electrolytes (sodium chloride, sodium bicarbonate, and potassium chloride) are added to the solution to help prevent electrolyte imbalances during the bowel cleansing process.
Common Dosages
- Powder for solution: Each container is reconstituted with 4 liters of water.
Typical Dosing
- Reconstitute the powder with 4 liters of water and chill the solution for better taste.
- Adults typically drink 240 mL (8 oz) of the solution every 10 to 15 minutes until approximately 4 liters are consumed, or until bowel movements are clear.
- The dosing schedule may be split into evening and morning doses or taken all at once, depending on healthcare provider instructions.
Typical Dosing
FDA Approved Indications
- Bowel cleansing prior to colonoscopy, barium enema X-rays, or other procedures requiring a clear view of the colon.
Who Shouldn't Take Nulytely Lemon-Lime?
- Bowel obstruction
- Known hypersensitivity to polyethylene glycol or any other components of the formulation
- Toxic colitis or megacolon
Advice From The Pharmacist
- Chill the solution to improve its taste and reduce any nausea or discomfort during consumption.
- Avoid solid foods at least 3-4 hours before starting Nulytely. A clear liquid diet (such as broth, tea, or clear juice) is typically recommended the day before your procedure.
- Stay close to a bathroom after starting Nulytely, as the bowel movements will become frequent and watery.
- Do not consume red or purple liquids, as they may interfere with the visibility of the colon during your procedure.
- Inform your healthcare provider if you experience signs of dehydration, such as dizziness or dry mouth.
Side Effects of Nulytely Lemon-Lime
Common Side Effects
- Nausea
- Abdominal bloating
- Cramping
- Vomiting
Uncommon/Severe Side Effects
- Dehydration
- Electrolyte imbalances leading to dizziness or irregular heartbeats
- Allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Nulytely Lemon-Lime
- Dehydration: Because Nulytely causes rapid fluid loss, it is important to stay well-hydrated with clear fluids throughout the preparation process.
- Electrolyte Imbalance: This is a potential risk, especially in patients with kidney disease or those taking medications that affect electrolyte levels. Inform your healthcare provider of all medications you're taking.
- Gastrointestinal Discomfort: Some patients may experience nausea, bloating, or cramping due to the large volume of fluid intake.
Interactions with Nulytely Lemon-Lime
Common Drug Interactions
- Diuretics: Can increase the risk of dehydration and electrolyte disturbances.
- NSAIDs: May affect kidney function, especially when combined with large amounts of fluid loss.
- ACE inhibitors and angiotensin receptor blockers (ARBs): Can also affect electrolyte balance when used with bowel cleansers.
Alternatives to Nulytely Lemon-Lime
- GoLYTELY®: Another PEG-based bowel cleansing solution similar to Nulytely.
- Miralax®: A lower-dose form of PEG 3350 used for occasional constipation rather than full bowel cleansing.
- Suprep®: A different bowel cleansing solution with a smaller volume requirement, used for the same purpose.
- MoviPrep®: A bowel preparation kit that involves taking two liters of solution.