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Nortrel 1/35 (28)

Nortrel 1/35 is an oral contraceptive that combines ethinyl estradiol (an estrogen) and norethindrone (a progestin) to prevent pregnancy. This formulation is designed to provide effective contraception and may also help regulate menstrual cycles and alleviate symptoms associated with menstruation.

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Frequently Asked Questions

How quickly does Nortrel 1/35 work?
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Nortrel 1/35 is effective after 7 days of consistent use. If you start taking it during the first 5 days of your menstrual cycle, it is effective immediately.

Can I take Nortrel 1/35 with food?
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Yes, it can be taken with or without food.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Are there any dietary restrictions while using Nortrel 1/35?
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There are no specific dietary restrictions while using Nortrel 1/35.

Is Nortrel 1/35 safe during pregnancy or breastfeeding?
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Nortrel 1/35 is not recommended during pregnancy. If you are breastfeeding, consult your healthcare provider about the best contraceptive options.

Comprehensive Drug Guide

How Does Nortrel 1/35 (28) Work?

  • Preventing ovulation (the release of an egg from the ovaries).
  • Thickening cervical mucus to inhibit sperm passage.
  • Altering the uterine lining to reduce the likelihood of implantation.


Common Dosages

  • Tablets: Each tablet contains 1 mg of norethindrone and 35 mcg of ethinyl estradiol.

Typical Dosing

  • The usual dosing regimen is one tablet taken orally once daily, preferably at the same time each day, for 28 days (21 active tablets followed by 7 inactive tablets).

Typical Dosing

FDA Approved Indications

  • Contraception: for the prevention of pregnancy.
  • Regulation of Menstrual Cycles: for managing menstrual disorders.


Who Shouldn't Take Nortrel 1/35 (28)?

  • Known hypersensitivity to any component of the formulation.
  • History of blood clots, certain cancers (e.g., breast cancer), liver disease, or uncontrolled high blood pressure.


Advice From The Pharmacist

  • Take Nortrel 1/35 as directed, and do not skip doses to maintain contraceptive effectiveness.
  • If you miss a dose, follow the instructions provided with the medication for missed doses.
  • Inform your healthcare provider of any other medications you are taking, as some can interact with hormonal contraceptives.


Side Effects of Nortrel 1/35 (28)

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Mood changes
  • Weight gain


Uncommon/Severe Side Effects

  • Blood clots (deep vein thrombosis, pulmonary embolism)
  • Severe headaches or migraines
  • Changes in vision or eye problems.


Risks and Warnings of Nortrel 1/35 (28)

  • Cardiovascular Risks: Increased risk of blood clots, especially in smokers and those over 35.
  • Regular Monitoring: Regular check-ups with a healthcare provider to monitor blood pressure and overall health are recommended.


Interactions with Nortrel 1/35 (28)

Common Drug Interactions

  • Antibiotics: Some antibiotics may reduce the effectiveness of hormonal contraceptives.
  • Anticonvulsants: Certain anticonvulsants can affect hormone levels and decrease contraceptive efficacy.


Alternatives to Nortrel 1/35 (28)

  • Other Combination Oral Contraceptives: Different brands or formulations with varying hormone levels.
  • Non-Hormonal Contraceptives: Such as copper intrauterine devices (IUDs) or barrier methods.