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Norgestimate-Eth Estradiol

Norgestimate-ethinyl estradiol is a combination oral contraceptive that includes norgestimate (a progestin) and ethinyl estradiol (an estrogen). It is primarily used for the prevention of pregnancy and can also help regulate menstrual cycles, treat acne, and manage symptoms of premenstrual syndrome (PMS).

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Frequently Asked Questions

How quickly does norgestimate-ethinyl estradiol work for contraception?
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Norgestimate-ethinyl estradiol provides contraceptive protection after 7 days of consistent use; it’s best to use additional contraception during this period.

Can I take norgestimate-ethinyl estradiol with food?
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Yes, it can be taken with or without food; however, consistency is key.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.

Are there any dietary restrictions while using norgestimate-ethinyl estradiol?
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There are no specific dietary restrictions while using this medication.

Is norgestimate-ethinyl estradiol safe during pregnancy or breastfeeding?
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Norgestimate-ethinyl estradiol should not be used during pregnancy. Consult your healthcare provider if you are breastfeeding to discuss its use.

Comprehensive Drug Guide

How Does Norgestimate-Eth Estradiol Work?

Norgestimate-ethinyl estradiol works by inhibiting ovulation, thickening cervical mucus to prevent sperm from reaching the egg, and altering the uterine lining to reduce the likelihood of implantation. This combination effectively prevents pregnancy and can also alleviate menstrual symptoms.

Common Dosages

  • Tablets: The specific formulation includes a combination of active and inactive tablets.

Typical Dosing

  • The usual regimen involves taking one tablet daily for 28 days, following the specific order of active and inactive tablets as indicated in the package instructions.


Typical Dosing

FDA Approved Indications

  • Contraception: for the prevention of pregnancy in females of reproductive age.
  • Acne Treatment: for the treatment of moderate acne in females 15 years and older who desire contraception.
  • PMS Management: to help manage symptoms associated with premenstrual syndrome.


Who Shouldn't Take Norgestimate-Eth Estradiol?

  • Known hypersensitivity to norgestimate, ethinyl estradiol, or any component of the formulation.
  • History of thromboembolic disorders (e.g., blood clots).
  • Severe liver disease or liver tumors.
  • Undiagnosed abnormal genital bleeding.


Advice From The Pharmacist

  • Take norgestimate-ethinyl estradiol exactly as prescribed, at the same time each day, to maintain consistent hormone levels.
  • If a dose is missed, follow the specific instructions provided with the medication for missed doses.
  • Regular check-ups may be necessary to monitor for side effects and ensure the effectiveness of the contraceptive.


Side Effects of Norgestimate-Eth Estradiol

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Mood changes
  • Spotting or breakthrough bleeding


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Symptoms of blood clots (pain, swelling in the legs, chest pain, shortness of breath).


Risks and Warnings of Norgestimate-Eth Estradiol

  • Cardiovascular Risks: There is an increased risk of thromboembolic events; patients should be assessed for risk factors.
  • Hormonal Effects: Monitor for mood changes and other hormonal side effects; discuss any concerns with your healthcare provider.


Interactions with Norgestimate-Eth Estradiol

Common Drug Interactions

  • Antibiotics: Some antibiotics may reduce the effectiveness of norgestimate-ethinyl estradiol; consult your healthcare provider for specific guidance.
  • Other Hormonal Contraceptives: Care should be taken when using multiple hormonal contraceptives concurrently.


Common Food Interactions


Alternatives to Norgestimate-Eth Estradiol

  • Other Oral Contraceptives: Such as those containing different combinations of estrogen and progestin.
  • Non-Hormonal Methods: Barrier methods or intrauterine devices (IUDs) may be considered for contraception.