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Nitro-Time
Nitro-Time (generic name: nitroglycerin) is a medication used primarily for the treatment and prevention of angina pectoris (chest pain) caused by coronary artery disease. It belongs to a class of drugs known as nitrates, which help to dilate blood vessels, improve blood flow to the heart, and reduce the heart's workload.
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Frequently Asked Questions
How quickly does Nitro-Time work?
Nitro-Time usually takes about 5 to 10 minutes to relieve angina symptoms when taken sublingually.
Can I take Nitro-Time with food?
Yes, Nitro-Time can be used with or without food; however, it is often taken sublingually at the onset of symptoms.
What should I do if I miss a dose?
If you miss a scheduled dose (for capsules or patches), take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Are there any dietary restrictions while using Nitro-Time?
There are no specific dietary restrictions while using Nitro-Time.
Is Nitro-Time safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Nitro-Time during these periods.
Comprehensive Drug Guide
How Does Nitro-Time Work?
Nitro-Time (generic name: nitroglycerin) is a medication used primarily for the treatment and prevention of angina pectoris (chest pain) caused by coronary artery disease. It belongs to a class of drugs known as nitrates, which help to dilate blood vessels, improve blood flow to the heart, and reduce the heart's workload.
Nitroglycerin works by releasing nitric oxide, which relaxes and dilates blood vessels (veins and arteries). This vasodilation reduces the amount of blood returning to the heart (preload) and decreases the heart's oxygen demand, alleviating angina symptoms.
Common Dosages
- Sublingual Tablets: usually 0.3 mg and 0.6 mg.
- Extended-Release Capsules: 2.5 mg, 6.5 mg, or other strengths.
- Transdermal Patches: various strengths.
Typical Dosing
- For acute angina, the sublingual tablet is taken as needed at the onset of angina symptoms.
- For extended-release capsules, the usual starting dose is 2.5 mg to 6.5 mg taken orally two to three times daily.
- The transdermal patch is typically applied once daily and worn for 12 to 14 hours before being removed.
Typical Dosing
FDA Approved Indications
- Angina Pectoris: for the prevention and treatment of angina attacks.
- Heart Failure: in some cases, to improve symptoms.
Who Shouldn't Take Nitro-Time?
- Known hypersensitivity to nitroglycerin or any component of the formulation.
- Severe anemia.
- Increased intracranial pressure or head trauma.
- Use of phosphodiesterase inhibitors (e.g., sildenafil) within 24 to 48 hours.
Advice From The Pharmacist
- Apply Nitro-Time ointment or patch to a clean, dry area of skin and avoid rubbing it in. Rotate application sites to minimize skin irritation.
- Store the medication in its original container, away from moisture and heat.
- Monitor for any signs of dizziness or headache, which are common side effects.
Side Effects of Nitro-Time
Common Side Effects
- Headache
- Dizziness or lightheadedness
- Flushing
- Nausea
- Skin irritation at the application site
Uncommon/Severe Side Effects
- Severe hypotension (low blood pressure)
- Syncope (fainting)
- Allergic reactions (rash, itching, swelling).
Risks and Warnings of Nitro-Time
- Blood Pressure Monitoring: Monitor blood pressure regularly, especially after initiating treatment or increasing dosage.
- Avoid Abrupt Discontinuation: Gradual withdrawal is recommended to prevent rebound angina.
Interactions with Nitro-Time
Common Drug Interactions
- Phosphodiesterase Inhibitors: Concurrent use with these medications can lead to severe hypotension.
- Antihypertensive Agents: May have additive effects, leading to increased risk of low blood pressure.
Alternatives to Nitro-Time
- Other Antianginal Agents: Such as beta-blockers or calcium channel blockers for managing angina.
- Long-Acting Nitrates: Other formulations of nitroglycerin for chronic management of angina.
