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Niacor
Niacor (generic name: niacin) is a form of vitamin B3 used primarily to help improve cholesterol levels and lower the risk of heart disease. It is effective in raising high-density lipoprotein (HDL) cholesterol while lowering low-density lipoprotein (LDL) cholesterol and triglycerides. Niacor is often prescribed as part of a comprehensive treatment plan that includes diet and exercise.
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Frequently Asked Questions
How quickly does Niacor work?
Patients may begin to see improvements in cholesterol levels within 4 to 12 weeks of starting treatment.
Can I take Niacor with food?
Yes, it is recommended to take Niacor with food to minimize gastrointestinal side effects.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using Niacor?
There are no specific dietary restrictions while using Niacor, but maintaining a heart-healthy diet is encouraged.
Is Niacor safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Niacor during these periods.
Comprehensive Drug Guide
How Does Niacor Work?
Niacin works by inhibiting the mobilization of free fatty acids from peripheral tissues, which decreases hepatic production of triglycerides and ultimately leads to lower levels of LDL cholesterol. It also increases the production of HDL cholesterol, which helps remove cholesterol from the bloodstream.
Common Dosages
- Tablets: Common strengths include 500 mg, 750 mg, and 1000 mg.
Typical Dosing
- For cholesterol management, the usual starting dose is 500 mg taken orally once daily, which may be gradually increased based on response and tolerability, with a maximum dose typically not exceeding 2000 mg per day.
Typical Dosing
FDA Approved Indications
- Hyperlipidemia: for the treatment of elevated cholesterol levels and to reduce the risk of cardiovascular events.
- Pellagra: for the treatment of niacin deficiency.
Who Shouldn't Take Niacor?
- Known hypersensitivity to niacin or any component of the formulation.
- Active liver disease or significant liver impairment.
- Severe peptic ulcer disease.
Advice From The Pharmacist
- Take Niacor with food to reduce gastrointestinal side effects.
- Monitor cholesterol levels regularly to assess the effectiveness of treatment.
- Report any unusual symptoms or side effects to your healthcare provider.
Side Effects of Niacor
Common Side Effects
- Flushing or warmth of the skin
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
Uncommon/Severe Side Effects
- Liver toxicity (elevated liver enzymes)
- Severe allergic reactions (rash, itching, swelling).
Risks and Warnings of Niacor
- Liver Function: Regular monitoring of liver function tests is recommended, especially at higher doses.
- Flushing: Flushing is a common side effect; consider taking an aspirin 30 minutes before the dose to help mitigate this reaction.
Interactions with Niacor
Common Drug Interactions
- Other Cholesterol-Lowering Medications: Caution is advised when used in conjunction with statins or other lipid-lowering agents, as there may be an increased risk of liver toxicity.
- Blood Pressure Medications: Monitor blood pressure regularly, as niacin can cause hypotension in some individuals.
Alternatives to Niacor
- Other Lipid-Lowering Agents: Such as statins or fibrates for managing cholesterol levels.
- Lifestyle Modifications: Dietary changes and increased physical activity to improve cholesterol levels.
