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Nexplanon
Nexplanon is a hormonal contraceptive implant that contains etonogestrel, a progestin. It is designed to prevent pregnancy for up to three years. Nexplanon is inserted under the skin of the upper arm and releases a steady dose of hormone to inhibit ovulation, thicken cervical mucus, and alter the uterine lining.
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Frequently Asked Questions
How quickly does Nexplanon work?
Nexplanon is effective immediately if inserted during the first five days of your menstrual cycle; otherwise, additional contraceptive methods should be used for the first seven days.
What should I do if I experience side effects?
Report any unusual or severe side effects, such as significant mood changes or symptoms of blood clots, to your healthcare provider.
Can Nexplanon be removed at any time?
Yes, Nexplanon can be removed by a healthcare provider at any time, and fertility will return quickly after removal.
Is Nexplanon safe during pregnancy?
Nexplanon is contraindicated during pregnancy; consult your healthcare provider for alternative contraceptive methods.
What are the signs of serious side effects to watch for?
Monitor for symptoms of severe allergic reactions or thromboembolic events, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Nexplanon Work?
- Suppressing ovulation (preventing the release of eggs from the ovaries).
- Thickening cervical mucus to block sperm from entering the uterus.
- Altering the endometrial lining, making it less suitable for implantation if fertilization occurs.
Common Dosages
- Implant: A single rod containing 68 mg of etonogestrel.
Typical Dosing
- Adults and Adolescents: The implant is inserted subdermally by a healthcare provider and is effective for up to three years. It can be removed earlier if pregnancy is desired or if side effects occur.
Typical Dosing
FDA Approved Indications
- The prevention of pregnancy in women of reproductive age.
Who Shouldn't Take Nexplanon?
- Known hypersensitivity to etonogestrel or any component of the formulation
- Current or history of thromboembolic disorders
- Severe liver disease or certain types of cancer (e.g., breast cancer)
Advice From The Pharmacist
- Ensure proper insertion by a qualified healthcare provider and discuss any concerns about the procedure.
- Monitor for side effects, particularly changes in menstrual patterns, mood changes, or signs of thromboembolic events.
- Inform your healthcare provider about any other medications you are taking, as some may interact with Nexplanon.
Side Effects of Nexplanon
Common Side Effects
- Irregular menstrual bleeding or spotting
- Headache
- Weight gain
- Mood changes
Uncommon/Severe Side Effects
- Signs of thromboembolic events (e.g., leg swelling, chest pain, sudden shortness of breath)
- Severe allergic reactions (rash, itching, swelling)
Risks and Warnings of Nexplanon
- Thromboembolic Risk: Monitor for signs of blood clots, especially in women with risk factors such as smoking or a history of clotting disorders.
- Hormonal Effects: Be aware of potential hormonal side effects and report any severe mood changes or symptoms of depression to your healthcare provider.
Interactions with Nexplanon
Common Drug Interactions
- CYP450 Inducers: Certain medications that induce liver enzymes may decrease the effectiveness of Nexplanon, including some anticonvulsants and herbal supplements like St. John's Wort.
Alternatives to Nexplanon
- Other Contraceptive Methods: Such as intrauterine devices (IUDs), hormonal pills, or other long-acting reversible contraceptives (LARCs).
- Non-hormonal Options: Such as barrier methods (condoms, diaphragms) for pregnancy prevention.
