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Natesto
Natesto (testosterone nasal gel) is a prescription medication used for the treatment of hypogonadism in men, a condition characterized by low testosterone levels. It is the first and only intranasal testosterone replacement therapy approved by the FDA.
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Frequently Asked Questions
How quickly does Natesto work?
Patients may start to notice improvements in symptoms within a few days, but it can take several weeks to achieve optimal testosterone levels.
Can I use Natesto with other medications?
Yes, but consult your healthcare provider to ensure safe and effective use alongside other treatments.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Is Natesto safe during pregnancy?
Natesto should not be used during pregnancy due to potential risks to the fetus.
What are the signs of serious side effects to watch for?
Monitor for signs of severe allergic reactions or changes in mood or behavior, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Natesto Work?
Natesto works by delivering testosterone directly through the nasal mucosa, allowing for rapid absorption into the bloodstream. This helps to restore testosterone levels to normal, alleviating symptoms associated with low testosterone, such as fatigue, depression, and reduced libido.
Common Dosages
- Nasal gel: Each pump delivers 4.5 mg of testosterone.
Typical Dosing
- Adults: The usual recommended dose is 1 pump (4.5 mg) in each nostril, administered twice daily for a total daily dose of 9 mg.
Typical Dosing
FDA Approved Indications
- Treatment of primary hypogonadism (congenital or acquired) and secondary hypogonadism (due to pituitary or hypothalamic disease) in men.
Who Shouldn't Take Natesto?
- Known hypersensitivity to testosterone or any component of the formulation.
- Male breast cancer or prostate cancer.
- Pregnant or breastfeeding women (due to potential harm to the fetus or infant).
Advice From The Pharmacist
- Use Natesto exactly as prescribed, and follow proper nasal administration techniques for optimal absorption.
- Avoid using Natesto in close proximity to others, particularly women and children, as testosterone can be transferred through skin contact or inhalation.
- Monitor for any changes in mood, behavior, or signs of increased testosterone levels, and report these to your healthcare provider.
Side Effects of Natesto
Common Side Effects
- Nasal irritation or discomfort
- Headache
- Increased nasal congestion
- Sore throat
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Increased risk of blood clots
- Changes in mood or behavior
Risks and Warnings of Natesto
- Cardiovascular Risks: Testosterone replacement therapy may increase the risk of cardiovascular events; discuss these risks with your healthcare provider.
- Monitor for Symptoms: Regular follow-up appointments to monitor testosterone levels and assess for potential side effects are important.
Interactions with Natesto
Common Drug Interactions
- Other Hormonal Medications: Inform your healthcare provider about all medications you are taking, especially those affecting hormone levels.
Alternatives to Natesto
- Other Testosterone Replacement Therapies: Such as intramuscular injections, transdermal patches, or topical gels.
- Non-hormonal Options: Depending on the underlying cause of symptoms, other treatments may be considered.
