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Morphine Sulfate ER Beads

Morphine Sulfate ER (Extended Release) Beads are a formulation of morphine sulfate, an opioid analgesic used for the management of severe pain that requires continuous, long-term opioid treatment. This formulation provides extended pain relief by releasing morphine gradually over time.



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Frequently Asked Questions

How quickly does Morphine Sulfate ER Beads work?
Open FAQClose FAQ

Morphine Sulfate ER Beads provide pain relief within several hours after administration, but the full effect may take a few days to stabilize.

Can I take Morphine Sulfate ER Beads with food?
Open FAQClose FAQ

Yes, it can be taken with or without food; however, consistency in how you take it is important.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Are there any dietary restrictions while using Morphine Sulfate ER Beads?
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There are no specific dietary restrictions, but monitor your fluid and fiber intake to help manage constipation.

Is Morphine Sulfate ER Beads safe during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Morphine Sulfate ER during these periods.

Comprehensive Drug Guide

How Does Morphine Sulfate ER Beads Work?

Morphine works by binding to specific receptors in the brain and spinal cord (mu-opioid receptors), blocking the perception of pain and altering the emotional response to pain. This action provides analgesia and helps alleviate suffering.



Common Dosages

  • Capsules: Common strengths include 15 mg, 30 mg, 60 mg, and 100 mg.

Typical Dosing

  • The usual starting dose varies depending on the patient's previous opioid exposure and the severity of pain. For patients who are opioid-naive, the starting dose is often 15 mg to 30 mg every 8 to 12 hours. The dosage may be adjusted based on pain control and tolerance.


Typical Dosing

FDA Approved Indications

  • Management of Severe Pain: for patients requiring continuous pain relief, such as those with cancer or chronic pain conditions.


Who Shouldn't Take Morphine Sulfate ER Beads?

  • Known hypersensitivity to morphine or any component of the formulation.
  • Severe respiratory depression or asthma.
  • Paralytic ileus or gastrointestinal obstruction.


Advice From The Pharmacist

  • Take Morphine Sulfate ER Beads exactly as prescribed, and do not exceed the recommended dose.
  • Swallow the capsules whole; do not crush or chew, as this can lead to rapid release and increased risk of overdose.
  • Monitor for signs of opioid-related side effects, including sedation and respiratory depression.


Side Effects of Morphine Sulfate ER Beads

Common Side Effects

  • Drowsiness or sedation
  • Constipation
  • Nausea and vomiting
  • Dizziness
  • Dry mouth


Uncommon/Severe Side Effects

  • Respiratory depression (slow or difficult breathing)
  • Severe allergic reactions (rash, itching, swelling)
  • Risk of overdose.


Risks and Warnings of Morphine Sulfate ER Beads

  • Respiratory Depression: Monitor closely for breathing difficulties, especially after initiating treatment or increasing dosage.
  • Addiction, Abuse, and Misuse: Assess for a history of substance use disorder and provide appropriate counseling on risks.


Interactions with Morphine Sulfate ER Beads

Common Drug Interactions

  • CNS Depressants: Use caution when combining with other central nervous system depressants (e.g., benzodiazepines, alcohol) as this may enhance sedative effects and increase the risk of respiratory depression.
  • MAO Inhibitors: Avoid use within 14 days of stopping monoamine oxidase inhibitors due to potential interactions.


Alternatives to Morphine Sulfate ER Beads

  • Other Opioid Analgesics: Such as oxycodone or hydromorphone for similar pain management.
  • Non-opioid Pain Relievers: Such as NSAIDs or acetaminophen for milder pain management.