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Mometasone Furoate

Mometasone furoate is a potent synthetic corticosteroid used to treat various inflammatory and allergic conditions. It is commonly used in formulations for nasal spray, topical cream, ointment, and inhalation. Mometasone works by reducing inflammation, itching, and swelling.



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Frequently Asked Questions

How quickly does mometasone furoate work?
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Patients may start to notice improvements in nasal symptoms within 1 to 2 days of starting treatment, with optimal effects typically seen after a few weeks.

Can I take mometasone furoate with food?
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Yes, mometasone can be taken with or without food, depending on the formulation.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Are there any dietary restrictions while using mometasone furoate?
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There are no specific dietary restrictions, but a balanced diet can help support overall health.

Is mometasone furoate safe during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using mometasone furoate.

Comprehensive Drug Guide

How Does Mometasone Furoate Work?

Mometasone furoate exerts its effects by binding to glucocorticoid receptors, leading to the suppression of inflammatory mediators and cytokines. This action helps decrease inflammation, reduce immune responses, and alleviate allergic symptoms.



Common Dosages

  • Nasal Spray: 50 mcg per spray.
  • Topical Cream/Ointment: 0.1%.
  • Inhalation Powder: 110 mcg and 220 mcg.

Typical Dosing

  • For allergic rhinitis: The usual dose for adults is 2 sprays in each nostril once daily.
  • For asthma: The usual dose is 200 mcg to 400 mcg once daily, depending on the specific inhaler formulation.
  • For topical use: Apply a thin layer to the affected area once daily.


Typical Dosing

FDA Approved Indications

  • Allergic Rhinitis: for the treatment of nasal symptoms associated with seasonal and perennial allergies.
  • Asthma: as a maintenance treatment to improve lung function and reduce symptoms.
  • Skin Conditions: for the treatment of inflammatory skin disorders such as eczema and psoriasis.
  • Sinusitis: for the management of nasal inflammation in sinusitis.


Who Shouldn't Take Mometasone Furoate?

  • Known hypersensitivity to mometasone or any component of the formulation.
  • Untreated bacterial, fungal, or viral infections.


Advice From The Pharmacist

  • Use mometasone furoate as prescribed and do not exceed the recommended dose.
  • For nasal sprays, prime the spray before use and avoid sneezing immediately after administration.
  • For topical applications, apply a thin layer and wash hands after use to prevent unwanted spread.


Side Effects of Mometasone Furoate

Common Side Effects

  • Nasal irritation or burning (for nasal spray)
  • Throat irritation (for inhalation)
  • Headache
  • Skin irritation or burning (for topical use)


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Adrenal suppression (with long-term use)
  • Increased risk of infections.


Risks and Warnings of Mometasone Furoate

  • Long-term Use: Prolonged use of corticosteroids can lead to systemic effects such as adrenal suppression and increased risk of infections; regular monitoring may be necessary.
  • Nasal and Ocular Effects: Use caution in patients with a history of nasal surgery or nasal ulcers, and monitor for changes in vision.


Interactions with Mometasone Furoate

Common Drug Interactions

  • Other Corticosteroids: Caution is advised when combining with other corticosteroids, as this may increase the risk of systemic effects.
  • Live Vaccines: Patients on systemic corticosteroids may have a reduced immune response; live vaccines should be avoided.


Alternatives to Mometasone Furoate

  • Other Intranasal Corticosteroids: Such as fluticasone propionate or budesonide for allergic rhinitis.
  • Non-Corticosteroid Options: Antihistamines or leukotriene receptor antagonists for allergy management.