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Moexipril HCl
Moexipril HCl is an angiotensin-converting enzyme (ACE) inhibitor used primarily to treat hypertension (high blood pressure). It helps lower blood pressure by relaxing blood vessels, making it easier for the heart to pump blood. This medication is often prescribed as part of a comprehensive treatment plan for patients with high blood pressure.
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Frequently Asked Questions
How quickly does moexipril HCl work?
Patients may begin to see a reduction in blood pressure within 1 to 2 weeks of starting treatment, but optimal control may take longer.
Can I take moexipril HCl with food?
Yes, moexipril can be taken with or without food.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using moexipril HCl?
There are no specific dietary restrictions, but monitoring potassium intake may be advisable.
Is moexipril HCl safe during pregnancy or breastfeeding?
Moexipril is generally not recommended during pregnancy and should be used with caution during breastfeeding; consult your healthcare provider for alternatives.
Comprehensive Drug Guide
How Does Moexipril HCl Work?
Moexipril works by inhibiting the action of the ACE enzyme, which is responsible for converting angiotensin I to angiotensin II, a substance that constricts blood vessels. By blocking this conversion, moexipril leads to vasodilation (widening of blood vessels), resulting in decreased blood pressure and reduced workload on the heart.
Common Dosages
- Tablets: 7.5 mg and 15 mg.
Typical Dosing
- The usual starting dose for adults is 7.5 mg taken orally once daily, which may be adjusted based on blood pressure response, with a maximum recommended dose of 15 mg per day.
Typical Dosing
FDA Approved Indications
- Hypertension: for the treatment of high blood pressure, either alone or in combination with other antihypertensive agents.
Who Shouldn't Take Moexipril HCl?
- Known hypersensitivity to moexipril or other ACE inhibitors.
- A history of angioedema related to previous ACE inhibitor therapy.
- Severe renal impairment or hyperkalemia (high potassium levels).
Advice From The Pharmacist
- Take moexipril exactly as prescribed, and monitor your blood pressure regularly.
- It may be taken with or without food; however, consistency is important.
- Be cautious when standing up quickly, as moexipril can cause dizziness or lightheadedness.
Side Effects of Moexipril HCl
Common Side Effects
- Dizziness
- Headache
- Fatigue
- Cough
- Nausea
Uncommon/Severe Side Effects
- Angioedema (swelling of the face, lips, or throat)
- Severe allergic reactions (rash, itching, difficulty breathing)
- Elevated potassium levels (hyperkalemia).
Risks and Warnings of Moexipril HCl
- Angioedema: Patients should be monitored for signs of swelling and report any such symptoms immediately.
- Renal Function: Regular monitoring of kidney function is advised, particularly in patients with pre-existing renal impairment.
- Electrolyte Imbalances: Monitor for changes in potassium levels, as ACE inhibitors can increase potassium concentrations.
Interactions with Moexipril HCl
Common Drug Interactions
- Potassium-Sparing Diuretics: Use caution when combining with potassium-sparing diuretics, as this may increase the risk of hyperkalemia.
- NSAIDs: Nonsteroidal anti-inflammatory drugs may reduce the antihypertensive effect of moexipril.
Alternatives to Moexipril HCl
- Other Antihypertensives: Such as angiotensin II receptor blockers (ARBs), calcium channel blockers, or diuretics for blood pressure management.
- Lifestyle Modifications: Diet, exercise, and weight management may also be recommended to help control hypertension.
