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Minocycline HCl ER
Minocycline HCl ER (extended-release) is a tetracycline antibiotic used to treat a variety of bacterial infections, including acne, respiratory tract infections, and skin infections. The extended-release formulation allows for once-daily dosing, improving patient compliance while effectively managing infections.
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Frequently Asked Questions
How quickly does minocycline HCl ER work?
Patients may start to see improvements in acne within a few weeks of starting treatment, although optimal results may take longer.
Can I take minocycline HCl ER with food?
Yes, it can be taken with or without food, but consistency in how you take it is important for absorption.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using minocycline HCl ER?
Avoid taking antacids or iron supplements within 2 hours of taking minocycline, as they can interfere with absorption.
Is minocycline HCl ER safe during pregnancy or breastfeeding?
Minocycline is generally not recommended during pregnancy or breastfeeding due to potential risks; consult your healthcare provider for alternatives.
Comprehensive Drug Guide
How Does Minocycline HCl ER Work?
Minocycline works by inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit, which prevents the growth and replication of bacteria. This action makes it effective against a wide range of Gram-positive and Gram-negative organisms.
Common Dosages
- Extended-Release Capsules: 135 mg.
Typical Dosing
- For acne treatment, the usual starting dose is 135 mg taken orally once daily, with adjustments based on individual response.
Typical Dosing
FDA Approved Indications
- Acne: for the treatment of moderate to severe acne.
- Bacterial Infections: including respiratory tract infections and skin infections.
Who Shouldn't Take Minocycline HCl ER?
- Known hypersensitivity to minocycline or other tetracycline antibiotics.
- Pregnancy or in children under 8 years of age due to the risk of teeth discoloration.
Advice From The Pharmacist
- Take minocycline HCl ER exactly as prescribed and do not exceed the recommended dose.
- It can be taken with or without food; however, taking it with food may help reduce gastrointestinal discomfort.
- Avoid taking antacids or iron supplements within 2 hours of taking minocycline, as they can interfere with absorption.
Side Effects of Minocycline HCl ER
Common Side Effects
- Dizziness
- Nausea
- Vomiting
- Diarrhea
- Skin rash
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis)
- Liver toxicity (symptoms include jaundice or dark urine)
- Increased intracranial pressure (symptoms include severe headache and vision changes).
Risks and Warnings of Minocycline HCl ER
- Photosensitivity: Minocycline may increase sensitivity to sunlight; patients should take precautions to avoid sun exposure.
- Teeth Discoloration: Use with caution in children and pregnant women, as tetracyclines can lead to permanent discoloration of teeth.
- Superinfection: Long-term use may result in the overgrowth of non-susceptible organisms, including fungi.
Interactions with Minocycline HCl ER
Common Drug Interactions
- Antacids: Containing aluminum, magnesium, or calcium can reduce the absorption of minocycline.
- Oral Contraceptives: Tetracyclines may decrease the effectiveness of hormonal contraceptives.
Alternatives to Minocycline HCl ER
- Other Tetracycline Antibiotics: Such as doxycycline for similar infections.
- Topical Treatments: For acne, topical antibiotics or retinoids may be considered.
