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Miglitol

Miglitol is an oral antidiabetic medication in the alphaglucosidase inhibitor class. It's used to manage blood glucose levels in those with type 2 diabetes. Some common side effects of Miglitol include gastrointestinal issues like diarrhea and flatulence, but your doctor will ensure the benefits outweigh these discomforts.

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Frequently Asked Questions

Can I just stop taking Miglitol after my sugar levels are stable?
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Not a good plan. Managing diabetes is a longterm effort and stopping your medication could result in your sugar levels rising again. Always consult your doctor before making any changes to your medication.

I missed a dose of Miglitol, what should I do?
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If you've missed a dose of miglitol, take it with your next meal unless it's near the time for your next dose. In that case, skip the missed dose and go back to your regular schedule.

Is weight gain a side effect of Miglitol?
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Unlike some other diabetes medications, miglitol is not usually associated with weight gain.

Comprehensive Drug Guide

How Does Miglitol Work?

Miglitol inhibits the action of alphaglucosidase in the intestine, an enzyme responsible for breaking down carbohydrates into individual sugar units. This prevents the rapid rise in blood glucose levels postmeals.

What is Miglitol Used For?

FDA indications: Miglitol is used, alongside a proper diet and exercise, for the treatment of type 2 diabetes. It's especially useful for managing postmeal hyperglycemia.

Common Dosages

Tablets: 25mg, 50mg, 100mg

Typical Dosing

FDA Approved Indications

  • The starting dose is usually 25mg three times a day with the first bite of each main meal.
  • The dose can be increased to 50mg or 100mg at four weeks depending on therapeutic response and tolerability.

Who Shouldn't Take Miglitol?

  • Have diabetic ketoacidosis or type 1 diabetes.
  • Have inflammatory bowel disease, colonic ulceration, or partial intestinal obstruction.
  • Have a known hypersensitivity to Miglitol.
  • Have severe kidney disease.

Advice From The Pharmacist

  • Take Miglitol at the beginning of each main meal.
  • Be alert to signs of hypoglycemia, especially if you're taking other diabetes medications.
  • It can cause gastrointestinal upset, particularly at the start of therapy.
  • Follow a consistent diet, avoid skipping meals, and monitor blood sugar regularly.
  • If you miss a dose, skip that dose and continue with the next tablet at the next meal.
  • If you experience severe diarrhea or similar gastrointestinal discomforts, let your doctor know.
  • Keep all your doctor's appointments and get regular checkups.

Side Effects of Miglitol

Common Side Effects

  • You may experience gastrointestinal issues like diarrhea, gas, and bloating.

Uncommon/Severe Side Effects

  • Uncommon side effects:
  • Mild skin rash or itching.
  • Rare side effects:
  • Signs of liver problems like dark urine, loss of appetite, stomach/abdominal pain, or yellowing eyes/skin.
  • Severe side effects:
  • If you have symptoms of hypoglycemia such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet, get medical help right away.

Risks and Warnings of Miglitol

  • Remember, Miglitol is not for type 1 diabetics or those with diabetic ketoacidosis.
  • Individuals with conditions like inflammatory bowel diseases or serious kidney dysfunction should avoid Miglitol.
  • Monitor your liver function regularly while taking Miglitol.

Interactions with Miglitol

Common Drug Interactions

  • Insulin and other antidiabetic drugs
  • Digestive enzymes

Alternatives to Miglitol

  • Acarbose
  • Voglibose