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Microgestin FE 1/20

Microgestin FE 1/20 is a combination oral contraceptive that contains ethinyl estradiol (a synthetic estrogen) and norethindrone acetate (a synthetic progestin). It is primarily used for the prevention of pregnancy but may also help regulate menstrual cycles and manage conditions like polycystic ovary syndrome (PCOS) and endometriosis.



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Frequently Asked Questions

How effective is Microgestin FE 1/20 as a contraceptive?
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When taken correctly, it is over 99% effective in preventing pregnancy.

Can I take Microgestin FE 1/20 if I smoke?
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Smoking increases the risk of serious cardiovascular side effects; it is generally advised to avoid using combined oral contraceptives if you smoke, especially if you are over 35.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Use backup contraception if you missed doses near the beginning or end of the pack.

Are there any dietary restrictions while using Microgestin FE 1/20?
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There are no specific dietary restrictions, but a balanced diet is advisable to support overall health.

Is Microgestin FE 1/20 safe during pregnancy or breastfeeding?
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Microgestin FE 1/20 is contraindicated during pregnancy and should be discussed with a healthcare provider if breastfeeding, as some hormones may be excreted in breast milk.

Comprehensive Drug Guide

How Does Microgestin FE 1/20 Work?

The combination of ethinyl estradiol and norethindrone works by preventing ovulation, altering the menstrual cycle, and thickening the cervical mucus to inhibit sperm passage. These actions together reduce the likelihood of pregnancy.


Common Dosages

  • Tablets: 1 mg norethindrone and 20 mcg ethinyl estradiol, with iron (ferrous fumarate) in the placebo tablets.

Typical Dosing

  • The typical dosing regimen is one tablet taken orally once daily at the same time each day for 21 days, followed by a 7-day break during which iron tablets are taken.

Typical Dosing

FDA Approved Indications

  • Contraception: prevention of pregnancy.
  • Regulation of Menstrual Cycles: management of irregular menstrual periods.
  • Management of Symptoms: associated with conditions such as endometriosis.


Who Shouldn't Take Microgestin FE 1/20?

  • Known hypersensitivity to any component of the formulation.
  • History of thromboembolic disorders or strokes.
  • Uncontrolled hypertension or severe cardiovascular conditions.
  • Certain cancers (e.g., breast cancer).


Advice From The Pharmacist

  • Take Microgestin FE 1/20 at the same time every day to maximize its effectiveness.
  • Inform your healthcare provider about any other medications or supplements you are taking, as they may interact with the contraceptive.
  • Monitor for side effects and contact your healthcare provider if you experience severe headaches, visual disturbances, or signs of a blood clot.


Side Effects of Microgestin FE 1/20

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headaches
  • Mood changes
  • Weight gain


Uncommon/Severe Side Effects

  • Blood clots (symptoms include swelling, pain, redness in the legs)
  • Liver dysfunction (symptoms include jaundice)
  • Hypertension


Risks and Warnings of Microgestin FE 1/20

  • Thromboembolic Events: Increased risk of blood clots; patients with risk factors should be closely monitored.
  • Liver Function: Regular liver function tests may be warranted in patients with existing liver issues.
  • Hormonal Side Effects: Some patients may experience significant mood changes or depressive symptoms.


Interactions with Microgestin FE 1/20

Common Drug Interactions

  • Antibiotics: Some antibiotics may reduce the effectiveness of hormonal contraceptives.
  • Anticonvulsants: Medications for epilepsy may also affect the effectiveness of the contraceptive.

Alternatives to Microgestin FE 1/20

  • Other Oral Contraceptives: Different formulations of combined or progestin-only pills may be suitable alternatives.
  • Long-Acting Reversible Contraceptives (LARCs): Such as IUDs or implants may be considered for those seeking longer-term contraception.