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M-M-R II

M-M-R II is a live attenuated vaccine that protects against three viral diseases: measles, mumps, and rubella. It is administered to children as part of the routine immunization schedule and is crucial in preventing outbreaks of these infectious diseases.



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Frequently Asked Questions

How effective is the M-M-R II vaccine?
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The M-M-R II vaccine is about 97% effective at preventing measles, 88% effective at preventing mumps, and 97% effective at preventing rubella after two doses.

Can M-M-R II cause the diseases it protects against?
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Because it contains live attenuated viruses, mild forms of the diseases can occur, but serious reactions are rare.

What should I do if my child misses a dose?
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If a dose is missed, schedule a vaccination as soon as possible. There is no need to restart the series if the schedule is missed.

Are there any special precautions after vaccination?
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M-M-R II is generally safe; however, if a rash or fever occurs, monitor the child and consult a healthcare provider if symptoms worsen.

Is M-M-R II safe during pregnancy?
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No, M-M-R II should not be administered during pregnancy. Women are advised to avoid becoming pregnant for at least four weeks after receiving the vaccine.

Comprehensive Drug Guide

How Does M-M-R II Work?

M-M-R II contains live, attenuated (weakened) viruses that stimulate the immune system to produce antibodies against measles, mumps, and rubella. This immune response provides protection against future infections by these viruses.



Common Dosages

  • Injection: Usually available in vials containing the vaccine.

Typical Dosing

  • The recommended schedule for children is:
  • First dose: Administered between 12 and 15 months of age.
  • Second dose: Administered between 4 and 6 years of age.


Typical Dosing

FDA Approved Indications

  • Immunization Against Measles: prevention of measles virus infection.
  • Immunization Against Mumps: prevention of mumps virus infection.
  • Immunization Against Rubella: prevention of rubella virus infection.

Who Shouldn't Take M-M-R II?

  • Severe allergic reactions to any component of the vaccine (including gelatin or neomycin).
  • Immunocompromised states (e.g., HIV infection with low CD4 counts).
  • Pregnancy (women should avoid becoming pregnant for at least four weeks after vaccination).


Advice From The Pharmacist

  • Ensure that the child is healthy at the time of vaccination; postpone if the child has a moderate or severe illness.
  • Inform the healthcare provider of any history of allergic reactions or immune system issues.
  • Keep the vaccination record updated and schedule follow-up doses as needed.


Side Effects of M-M-R II

Common Side Effects

  • Fever
  • Rash
  • Mild pain at the injection site
  • Swelling of lymph nodes


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Thrombocytopenia (low platelet count).


Risks and Warnings of M-M-R II

  • Immunocompromised Individuals: Individuals with weakened immune systems should avoid contact with recently vaccinated individuals if there is a possibility of transmission.
  • Pregnancy: Women should avoid becoming pregnant for at least four weeks following vaccination.

Interactions with M-M-R II

Common Drug Interactions

  • Immunosuppressive Therapies: Consult a healthcare provider if the individual is receiving treatments that suppress the immune system, as this can affect vaccine efficacy.

Alternatives to M-M-R II

  • Alternative Vaccines: Combination vaccines that include protection against additional diseases (e.g., MMRV for measles, mumps, rubella, and varicella).