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Lucemyra

Lucemyra is also sold under the generic name Lofexidine. It's a nonopioid medication designed to help reduce the discomfort associated with opioid withdrawal, such as feelings of coldness, chills, yawning, and goose skin. Some common side effects include low blood pressure, slow heart rate, sleepiness, and dry mouth. Always follow your doctor's advice when taking Lucemyra.

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Frequently Asked Questions

Can I take Lucemyra if I am pregnant or breastfeeding?
Open FAQClose FAQ

The effects of Lucemyra on an unborn or nursing infant are unknown. If you are pregnant, planning to be pregnant, or nursing, consult your healthcare provider before starting this medication.

What happens if I miss a dose?
Open FAQClose FAQ

If you forget to take Lucemyra, just take the next dose at your usual time. Do not ?double up? doses to make up for the one that you missed.

Will Lucemyra cure my opioid addiction?
Open FAQClose FAQ

No. Lucemyra only helps with physical withdrawal symptoms. It does not treat the psychological aspects of addiction. It should be used as part of a comprehensive recovery program that includes counseling and other behavioral therapies.

Comprehensive Drug Guide

How Does Lucemyra Work?

Lucemyra is a selective alpha2adrenergic receptor agonist that reduces norepinephrine release in the brain and thereby diminishes the 'fight or flight' signals, leading to reduced withdrawal symptoms.

What is Lucemyra Used For?

FDA indications: Lucemyra is used to manage the physical symptoms of opioid withdrawal.

Offlabel uses: None known. Lucemyra is highly specialized for opioid withdrawal symptoms and should not be used outside this context.

Common Dosages

Tablets: 0.18 mg

Typical Dosing

FDA Approved Indications

  • Opioid withdrawal: The initial dosage is generally three 0.18 mg tablets taken orally four times daily during the period of peak withdrawal symptoms (57 days following last opioid use)

Who Shouldn't Take Lucemyra?

  • If you have severe liver disease or significant heart disease.
  • Are taking medications that reduce your heart rate or blood pressure?
  • Are pregnant or nursing, or plan to become pregnant.
  • Have improper functioning of the kidneys or adrenal gland.
  • If you're allergic to it or its family of drugs.

Advice From The Pharmacist

  • Take with or without food, but whichever one you choose, stick to it.
  • Don't stop taking Lucemyra suddenly before completing the full treatment plan because this could make your withdrawal symptoms worsen.
  • Be cautious while driving or doing anything that requires focus as Lucemyra can cause drowsiness.
  • Drink plenty of fluids to manage a potential side effect of dry mouth.
  • Check regularly with your doctor and report any symptoms or side effects promptly.

Side Effects of Lucemyra

Common Side Effects

  • Low blood pressure.
  • Slowed heart rate.
  • You might feel sleepiness or have trouble sleeping.
  • You might feel dizzy, especially when going from lying or sitting to standing.

Uncommon/Severe Side Effects

  • Uncommon side effects:
  • You might have a dry mouth or feel dehydrated.
  • Rare side effects:
  • You might develop irregular heart rhythms.
  • Severe side effects:
  • Experience fainting or major dizziness.
  • Rapid or irregular heart beating.
  • Signs of a severe allergic reaction require immediate medical attention. These may include a rash, itching or swelling of the face, throat, or tongue, severe dizziness, and difficulty breathing.

Risks and Warnings of Lucemyra

  • Don't drive or operate heavy machinery until you know how Lucemyra affects you.
  • People with low heart rate should not use Lucemyra unless prescribed by the doctor, lest their condition worsens.
  • People with kidney or liver problems should use Lucemyra with caution.

Interactions with Lucemyra

Common Drug Interactions

  • Clonidine
  • Antihypertensives
  • Betablockers
  • CNS depressants
  • Heart medications

Alternatives to Lucemyra

  • Clonidine
  • Methadone
  • Naltrexone
  • Buprenorphine
  • Methadone