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Loestrin 1.5/30 (21)
Loestrin 1.5/30 is a combination oral contraceptive that contains ethinyl estradiol (30 mcg) and norethindrone acetate (1.5 mg). This formulation is primarily used for the prevention of pregnancy and may also help regulate menstrual cycles and manage menstrual disorders. The 21-day dosing schedule allows for a consistent hormonal intake.
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Frequently Asked Questions
How effective is Loestrin 1.5/30 at preventing pregnancy?
When taken as directed, Loestrin 1.5/30 is over 99% effective at preventing pregnancy.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Can I use Loestrin 1.5/30 while breastfeeding?
Consult your healthcare provider about the use of hormonal contraceptives while breastfeeding, as some may not be recommended.
Will Loestrin 1.5/30 affect my menstrual cycle?
Some women experience lighter periods or changes in their menstrual cycle while using Loestrin 1.5/30.
Is it safe to smoke while taking Loestrin 1.5/30?
Smoking increases the risk of serious cardiovascular side effects. It is advisable to quit smoking before starting any hormonal contraceptive.
Comprehensive Drug Guide
How Does Loestrin 1.5/30 (21) Work?
Loestrin 1.5/30 works primarily by preventing ovulation through the inhibition of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It also thickens cervical mucus, making it difficult for sperm to enter the uterus, and alters the endometrial lining to reduce the likelihood of implantation.
Common Dosages
- Active Tablets: 30 mcg of ethinyl estradiol and 1.5 mg of norethindrone.
- Inactive Tablets: This formulation does not include inactive tablets as it follows a 21-day regimen.
Typical Dosing
- Take one active tablet daily for 21 days. After completing the 21 days, a new pack should be started without interruption.
- It is important to take the tablets at the same time each day for maximum effectiveness.
Typical Dosing
FDA Approved Indications
- Prevention of Pregnancy: as an oral contraceptive.
- Management of Menstrual Disorders: to help regulate menstrual cycles and alleviate symptoms like heavy bleeding.
Who Shouldn't Take Loestrin 1.5/30 (21)?
- Known hypersensitivity to ethinyl estradiol, norethindrone, or any component of the formulation.
- History of thromboembolic disorders (such as deep vein thrombosis or pulmonary embolism).
- Severe liver disease or liver tumors.
- Certain cancers, such as breast cancer.
Advice From The Pharmacist
- Use a backup contraceptive method (e.g., condoms) during the first 7 days of starting Loestrin 1.5/30 if it is your first time using hormonal contraception.
- Inform your healthcare provider of any other medications you are taking, as some can interact with Loestrin 1.5/30.
- Monitor for any unusual side effects and report them to your healthcare provider.
Side Effects of Loestrin 1.5/30 (21)
Common Side Effects
- Nausea
- Breast tenderness
- Headaches
- Mood changes
- Spotting or breakthrough bleeding
Uncommon/Severe Side Effects
- Signs of a blood clot (swelling, pain in the legs, sudden shortness of breath).
- Severe headaches or vision changes.
- Signs of liver dysfunction (jaundice, severe abdominal pain).
Risks and Warnings of Loestrin 1.5/30 (21)
- Cardiovascular Risk: Hormonal contraceptives can increase the risk of blood clots, especially in smokers and women over 35.
- Liver Health: Regular monitoring may be required for women with liver issues.
- Missed Doses: Be aware of what to do if you miss a dose, as this can affect contraceptive effectiveness.
Interactions with Loestrin 1.5/30 (21)
Common Drug Interactions
- Antibiotics: Some antibiotics may reduce the effectiveness of Loestrin 1.5/30.
- Antiepileptic Drugs: Certain medications for seizures can affect hormone levels.
- St. John’s Wort: This herbal supplement may decrease the effectiveness of hormonal contraceptives.
Alternatives to Loestrin 1.5/30 (21)
- Other Oral Contraceptives: Different formulations may be recommended based on individual health needs and side effects.
- Long-Acting Reversible Contraceptives (LARCs): Such as IUDs or implants.
- Barrier Methods: Such as condoms or diaphragms for contraception.
