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Levsin/SL
Levsin/SL (hyoscyamine sulfate) is an anticholinergic medication used to treat various gastrointestinal disorders, including irritable bowel syndrome (IBS) and other conditions that cause excessive stomach acid and cramping. It helps relieve symptoms such as abdominal pain, cramping, and gastrointestinal spasms.
Levsin/SL is available by prescription and is not classified as a controlled substance. It is typically provided in sublingual tablet form.
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Frequently Asked Questions
How long does it take for Levsin/SL to start working?
Levsin/SL typically begins to relieve symptoms within 15 to 30 minutes of administration.
Can I take Levsin/SL with other medications?
Always consult your healthcare provider before combining Levsin/SL with other medications, especially other anticholinergics.
What should I do if I miss a dose of Levsin/SL?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take extra.
Is it safe to use Levsin/SL during pregnancy?
Levsin/SL should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Levsin/SL cause weight gain?
Weight gain is not typically associated with Levsin/SL, but any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Levsin/SL Work?
Hyoscyamine works by blocking the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the central nervous system. This results in decreased muscle spasms in the gastrointestinal tract and reduced secretions, leading to symptom relief.
Common Dosages
The usual dosage for adults is 1 sublingual tablet taken as needed, typically every 4 to 6 hours, not to exceed 12 tablets per day.
Typical Dosing
FDA Approved Indications
- Treatment of irritable bowel syndrome (IBS).
- Management of gastrointestinal disorders that involve muscle spasms.
Who Shouldn't Take Levsin/SL?
- Known hypersensitivity to hyoscyamine or any components of the formulation
- Glaucoma
- Myasthenia gravis
- Severe ulcerative colitis
- Gastrointestinal obstruction
Advice From The Pharmacist
- Patients should be advised to place the tablet under the tongue and allow it to dissolve completely for optimal absorption.
- Discuss the importance of adhering to the prescribed dosing schedule and not exceeding the maximum daily limit.
- Encourage patients to report any unusual symptoms, such as blurred vision or difficulty urinating.
Side Effects of Levsin/SL
Common Side Effects
- Dry mouth
- Dizziness
- Drowsiness
- Constipation
- Blurred vision
Uncommon/Severe Side Effects
- Rapid heart rate (tachycardia)
- Severe allergic reactions (anaphylaxis)
- Confusion or hallucinations, especially in the elderly
Risks and Warnings of Levsin/SL
- Caution in Elderly Patients: Older adults may be more sensitive to the effects of anticholinergics and should be monitored closely.
- Gastrointestinal Obstruction: Use with caution in patients with a history of gastrointestinal obstruction or other related conditions.
Interactions with Levsin/SL
Common Drug Interactions
- Other Anticholinergics: Caution is advised when used with other medications that have anticholinergic properties, as this may increase side effects.
- Medications Affecting Heart Rate: Monitor patients closely when used in conjunction with other medications that may affect heart rhythm.
Alternatives to Levsin/SL
- Other Antispasmodics: Such as dicyclomine for similar indications.
- Dietary Changes: May be recommended for managing IBS symptoms, alongside or instead of medication.
