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Levonorgestrel-Ethinyl Estradiol
Levonorgestrel-ethinyl estradiol is a combination oral contraceptive that contains levonorgestrel, a progestin, and ethinyl estradiol, an estrogen. It is primarily used for the prevention of pregnancy and may also help regulate menstrual cycles and alleviate symptoms associated with menstruation, such as acne and dysmenorrhea.
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Frequently Asked Questions
How long does it take for levonorgestrel-ethinyl estradiol to be effective?
Levonorgestrel-ethinyl estradiol is typically effective within 7 days if taken as directed. Backup contraception is recommended during this time.
Can I take levonorgestrel-ethinyl estradiol with other medications?
Always consult your healthcare provider before combining levonorgestrel-ethinyl estradiol with other medications, especially those that may affect its effectiveness.
What should I do if I miss a dose of levonorgestrel-ethinyl estradiol?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Is it safe to use levonorgestrel-ethinyl estradiol during pregnancy?
Levonorgestrel-ethinyl estradiol is contraindicated during pregnancy; women of childbearing age should use effective contraception while on this medication.
Can levonorgestrel-ethinyl estradiol cause weight gain?
Weight gain is a possible side effect of hormonal contraceptives. Any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Levonorgestrel-Ethinyl Estradiol Work?
- Inhibiting Ovulation: Preventing the release of eggs from the ovaries.
- Thickening Cervical Mucus: Making it more difficult for sperm to enter the uterus.
- Altering the Uterine Lining: Making it less suitable for implantation.
Common Dosages
- Tablets: Common dosages may include varying combinations of levonorgestrel and ethinyl estradiol, such as 0.15 mg of levonorgestrel and 0.03 mg of ethinyl estradiol.
Typical Dosing
- The usual dosage is one tablet taken orally once daily, starting on the first day of the menstrual cycle or as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy.
- Management of menstrual-related disorders, such as irregular cycles or painful periods.
Who Shouldn't Take Levonorgestrel-Ethinyl Estradiol?
- Known hypersensitivity to levonorgestrel, ethinyl estradiol, or any components of the formulation
- History of thromboembolic disorders (e.g., blood clots)
- Uncontrolled hypertension or liver disease
- Certain types of cancers (e.g., estrogen-sensitive tumors)
Advice From The Pharmacist
- Patients should be advised to take levonorgestrel-ethinyl estradiol at the same time each day to maintain consistent hormone levels.
- Discuss the importance of backup contraception if a dose is missed or taken late.
- Encourage patients to report any unusual symptoms, such as severe headaches, leg swelling, or vision changes.
Side Effects of Levonorgestrel-Ethinyl Estradiol
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Mood changes
- Weight gain
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis or pulmonary embolism)
- Stroke
- Liver tumors
Risks and Warnings of Levonorgestrel-Ethinyl Estradiol
- Cardiovascular Risks: Monitor patients with risk factors for cardiovascular disease, such as smoking or a history of hypertension.
- Regular Check-ups: Routine follow-ups with healthcare providers are important for monitoring overall health while on hormonal contraceptives.
Interactions with Levonorgestrel-Ethinyl Estradiol
Common Drug Interactions
Other Medications: Certain medications (e.g., antibiotics, anticonvulsants) may reduce the effectiveness of levonorgestrel-ethinyl estradiol. Consult a healthcare provider about potential interactions.
Alternatives to Levonorgestrel-Ethinyl Estradiol
- Other Oral Contraceptives: Different combinations of estrogen and progestin may be considered based on individual health needs.
- Non-Hormonal Methods: Such as condoms or copper intrauterine devices (IUDs) for contraception.
