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Levocetirizine Dihydrochloride

Levocetirizine is the active ingredient in Xyzal, a second-generation non-sedating antihistamine. It's used primarily for the relief of symptoms associated with allergies such as sneezing, itching, runny nose, and watery eyes. While most people tolerate Levocetirizine well, potential side effects can include drowsiness and dry mouth.

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Frequently Asked Questions

Can I take levocetirizine if I'm pregnant or breastfeeding?
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It's generally safe, but you should still consult with your healthcare provider.

Does levocetirizine cause drowsiness?
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While it's classified as a non-drowsy antihistamine, it can still cause drowsiness in some people.

Can I drink alcohol while taking levocetirizine?
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It's best to avoid alcohol while taking levocetirizine as it can increase the risk of side effects like drowsiness and dizziness.

If I miss a dose of levocetirizine, what should I do?
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Try to take it as soon as you remember. But if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Don't double up.

Comprehensive Drug Guide

How Does Levocetirizine Dihydrochloride Work?

Levocetirizine is a selective and potent peripheral H1-blocker. It blocks the effects of histamine in the body, thus reducing the symptoms of allergies.


What is Levocetirizine Dihydrochloride Used For?

Levocetirizine is used to help relieve allergy symptoms hives, seasonal allergic nasal congestion, runny nose, sneezing, and respiratory tract allergies.


Common Dosages

Tablets: 5mg 


Typical Dosing

FDA Approved Indications

Allergy symptoms: 2.5 to 5mg per day. If symptoms persist after 2 weeks, can increase up to 4 times standard dose.

Who Shouldn't Take Levocetirizine Dihydrochloride?

  • People who are allergic to levocetirizine, cetirizine, hydroxyzine, or any ingredients of the medication.
  • People with severe kidney problems.


Advice From The Pharmacist

  • Try to take levocetirizine at the same time each day to help you remember it.
  • Levocetirizine can be taken with or without food.
  • Although levocetirizine is a non-drowsy antihistamine, it can still make some people feel sleepy. Be cautious before you drive or operate machinery until you know how this medicine affects you.


Side Effects of Levocetirizine Dihydrochloride

Common Side Effects

  • Drowsiness, tiredness, dry mouth, constipation, diarrhea


Uncommon/Severe Side Effects

  • Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

Risks and Warnings of Levocetirizine Dihydrochloride

  • Levocetirizine might not be suitable for people with certain conditions or those taking specific medications. Consult with your healthcare provider if you:
  • Have kidney disease
  • Are pregnant or breastfeeding
  • Are over 65 years of age (you may be more susceptible to the side effects)


Interactions with Levocetirizine Dihydrochloride

Common Drug Interactions

  • Lacosamide
  • Sodium Oxybate
  • Meperidine
  • Codeine


Alternatives to Levocetirizine Dihydrochloride

  • Cetirizine
  • Loratadine
  • Fexofenadine
  • Desloratadine