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Kyleena
Kyleena is a levonorgestrel-releasing intrauterine system (IUS) used for long-term contraception. It is a small, T-shaped device that is inserted into the uterus, where it slowly releases the hormone levonorgestrel to prevent pregnancy. Kyleena is effective for up to 5 years and provides highly effective, reversible birth control. It is one of the smallest IUDs available and is suitable for women who have or have not had children.
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Frequently Asked Questions
How effective is Kyleena?
Kyleena is over 99% effective at preventing pregnancy, making it one of the most reliable forms of contraception available.
Can I get pregnant immediately after removing Kyleena?
Yes, fertility typically returns quickly after Kyleena is removed, and you can become pregnant as soon as it is taken out.
Can I use tampons or menstrual cups with Kyleena?
Yes, tampons and menstrual cups can be safely used with Kyleena, but be careful not to pull on the IUD strings when removing them.
How soon after insertion does Kyleena start working?
Kyleena is effective immediately if inserted within the first 7 days of your menstrual cycle. If inserted at another time, use backup contraception for the first 7 days after insertion.
Can I use Kyleena if I haven’t had children?
Yes, Kyleena is suitable for women who have not had children as well as those who have. Its smaller size makes it a good option for women who haven’t given birth.
Comprehensive Drug Guide
How Does Kyleena Work?
- Thickening cervical mucus, making it difficult for sperm to reach and fertilize an egg.
- Thinning the uterine lining, which may prevent implantation of a fertilized egg.
- In some cases, inhibiting ovulation.
These combined mechanisms make Kyleena a highly effective form of birth control.
Common Dosages
- Kyleena is a 52 mg intrauterine system that releases about 17.5 micrograms of levonorgestrel per day at the start and gradually decreases to about 7.4 micrograms per day over 5 years.
Typical Dosing
- Kyleena is a single-use device inserted into the uterus by a healthcare provider. It is designed to provide contraception for up to 5 years. After this period, it should be removed or replaced by a new device if continued contraception is desired.
Typical Dosing
FDA Approved Indications
- Long-term contraception (birth control) for up to 5 years.
Who Shouldn't Take Kyleena?
- Active pelvic infections (e.g., pelvic inflammatory disease)
- Uterine abnormalities that distort the shape of the uterus
- Unexplained vaginal bleeding
- Breast cancer or any hormone-sensitive cancers
- Known hypersensitivity or allergy to levonorgestrel or any of the components of the device
Advice From The Pharmacist
- Insertion and removal of Kyleena should only be done by a trained healthcare provider.
- Check the strings of Kyleena regularly (usually once a month) to ensure it is still in place. Your healthcare provider will teach you how to do this.
- If you experience severe pain, fever, unusual vaginal discharge, or suspect that Kyleena has moved out of place, contact your doctor immediately.
- Spotting or irregular bleeding is common in the first 3 to 6 months after insertion, but it usually improves over time.
- Kyleena does not protect against sexually transmitted infections (STIs). Use condoms to reduce the risk of STIs.
Side Effects of Kyleena
Common Side Effects
- Irregular bleeding or spotting, especially in the first 3 to 6 months
- Pelvic pain or cramping during or after insertion
- Ovarian cysts
- Headache
- Acne
- Breast tenderness
Uncommon/Severe Side Effects
- Pelvic inflammatory disease (PID)
- Ectopic pregnancy (pregnancy outside the uterus)
- Uterine perforation (rare but serious complication during insertion)
- Device expulsion (where the IUD moves out of place or falls out)
Risks and Warnings of Kyleena
- Pelvic Infections: Kyleena users are at a slightly increased risk of developing pelvic inflammatory disease (PID), especially in the first few weeks after insertion. Report any signs of infection, such as fever or unusual vaginal discharge, to your healthcare provider.
- Uterine Perforation: Rarely, insertion of Kyleena can cause uterine perforation, which may require surgery to remove the device. This risk is higher in breastfeeding women.
- Ectopic Pregnancy: Although rare, if pregnancy occurs while using Kyleena, there is an increased risk that it could be an ectopic pregnancy (a pregnancy outside the uterus). This condition requires immediate medical attention.
- Expulsion: Kyleena may be partially or completely expelled from the uterus, especially in younger women or those who have not had children. If this occurs, contraception is no longer effective.
Interactions with Kyleena
Common Drug Interactions
- Kyleena is a local contraceptive and is not significantly affected by interactions with other medications. However, certain medications that affect hormone metabolism could theoretically reduce its effectiveness, though this is rare. Always inform your healthcare provider about any other medications or supplements you are taking.
Alternatives to Kyleena
- Mirena: Another levonorgestrel-releasing IUS that lasts for up to 6 years.
- Skyla: A smaller IUD with a lower dose of levonorgestrel that lasts for up to 3 years.
- Paragard: A non-hormonal copper IUD that provides contraception for up to 10 years.
- Nexplanon: A progestin-only implant inserted under the skin of the upper arm, effective for up to 3 years.
