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Kenalog-80

Kenalog-80 (triamcinolone acetonide) is a corticosteroid used to reduce inflammation and suppress the immune response in various conditions. It is commonly used for the treatment of allergic reactions, skin disorders, arthritis, and other inflammatory conditions. The formulation is typically administered via injection.

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Frequently Asked Questions

How long does it take for Kenalog-80 to start working?
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Patients may begin to notice relief from inflammation within 24 to 72 hours after injection, but the full effect may take longer.

Can I take Kenalog-80 with other medications?
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Always consult your healthcare provider before combining Kenalog-80 with other medications, especially immunosuppressants or anticoagulants.

What should I do if I miss a dose of Kenalog-80?
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If you miss a scheduled injection, contact your healthcare provider to determine the best course of action.

Is it safe to use Kenalog-80 during pregnancy?
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Kenalog-80 should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.

Can Kenalog-80 cause weight gain?
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Weight gain is a common side effect of corticosteroids like Kenalog-80. Any significant changes in weight should be discussed with a healthcare provider.

Comprehensive Drug Guide

How Does Kenalog-80 Work?

Triamcinolone acetonide works by binding to glucocorticoid receptors in target tissues, leading to the modulation of gene expression. This results in decreased production of pro-inflammatory mediators, suppression of immune responses, and reduced inflammation, thereby alleviating symptoms associated with various conditions.

Common Dosages

  • Injectable suspension: Contains 80 mg of triamcinolone acetonide per mL.

Typical Dosing

  • The usual dosage varies based on the condition being treated. For intra-articular injections, the typical dose may range from 10 mg to 80 mg, depending on the joint size and severity of inflammation.
  • For other indications, dosing will depend on the specific clinical situation and should be determined by a healthcare provider.


Typical Dosing

FDA Approved Indications

  • Relief of inflammatory conditions such as arthritis, dermatitis, and allergic reactions.
  • Management of certain skin diseases and conditions affecting joints.


Who Shouldn't Take Kenalog-80?

  • Known hypersensitivity to triamcinolone or any components of the formulation
  • Systemic fungal infections
  • Active infections, as corticosteroids may exacerbate infections


Advice From The Pharmacist

  • Patients should be advised about potential side effects, including weight gain, fluid retention, and increased blood sugar levels.
  • Encourage patients to follow up regularly with their healthcare provider to monitor response to treatment and any potential side effects.
  • Advise patients to report any signs of infection, such as fever or unusual swelling, especially following an injection.


Side Effects of Kenalog-80

Common Side Effects

  • Injection site pain or irritation
  • Weight gain
  • Increased appetite
  • Mood changes


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Infections
  • Changes in vision (e.g., cataracts, glaucoma)


Risks and Warnings of Kenalog-80

  • Infection Risk: Caution is advised in patients with a history of recurrent infections, as corticosteroids can suppress the immune system.
  • Metabolic Effects: Regular monitoring of blood glucose levels is important, especially in patients with diabetes.


Interactions with Kenalog-80

Common Drug Interactions

  • Live Vaccines: Caution is advised when administering live vaccines to patients receiving corticosteroids due to the risk of infection.
  • Anticoagulants: Increased monitoring may be necessary if corticosteroids are used with blood thinners.


Alternatives to Kenalog-80

  • Other Corticosteroids: Such as dexamethasone or prednisone, depending on the condition being treated.
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs): For managing pain and inflammation in conditions like arthritis.