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Kariva

Kariva is a combination oral contraceptive that contains ethinyl estradiol and desogestrel. It is primarily used for the prevention of pregnancy and can also help regulate menstrual cycles, reduce menstrual cramps, and manage conditions such as acne in women who desire contraception. Kariva is designed to provide effective birth control while minimizing the frequency of menstrual periods through its extended-cycle regimen.

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Frequently Asked Questions

How effective is Kariva at preventing pregnancy?
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Kariva is over 99% effective when taken correctly. Missing pills or inconsistent use can reduce its effectiveness.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember and continue with your regular schedule. If you miss two or more pills, follow the instructions in the package insert and use backup contraception for the next 7 days.

Can Kariva help regulate my menstrual cycle?
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Yes, Kariva can help regulate your period and reduce the severity of menstrual cramps.

Can Kariva be used to treat acne?
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Yes, Kariva may help manage acne in women who also desire oral contraception.

Is Kariva safe for long-term use?
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Kariva can be safe for long-term use under the supervision of a healthcare provider, with regular monitoring for any potential side effects.

Comprehensive Drug Guide

How Does Kariva Work?

  1. Prevention of ovulation: The hormones in Kariva inhibit the release of eggs from the ovaries.
  2. Thickening of cervical mucus: This makes it more difficult for sperm to enter the uterus.
  3. Alteration of the uterine lining: The lining becomes less suitable for implantation, thus reducing the likelihood of pregnancy.

Common Dosages

  • 21 active pills: Each containing 0.15 mg of desogestrel and 0.02 mg of ethinyl estradiol.
  • 7 inactive pills: Taken during the last week to allow for a withdrawal bleed.

Typical Dosing

  • For contraception: Take 1 active pill daily for 21 consecutive days, followed by 1 inactive pill daily for the next 7 days. A withdrawal bleed usually occurs during this time.

Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy
  • Management of menstrual-related symptoms
  • Regulation of menstrual cycles

Who Shouldn't Take Kariva?

  • Known hypersensitivity to ethinyl estradiol, desogestrel, or any components of the formulation.
  • History of blood clots, deep vein thrombosis (DVT), or pulmonary embolism (PE).
  • Uncontrolled high blood pressure or certain types of cancers (e.g., breast cancer).
  • Liver disease or liver tumors.

Advice From The Pharmacist

  • Take Kariva at the same time every day to ensure maximum effectiveness.
  • If you miss a pill, follow the instructions in the package insert or contact your healthcare provider for guidance.
  • Kariva does not protect against sexually transmitted infections (STIs); use condoms to reduce the risk of STIs.
  • Some women may experience spotting or breakthrough bleeding during the first few months of use, which typically resolves as the body adjusts to the hormones.

Side Effects of Kariva

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Mood changes
  • Weight fluctuations
  • Spotting or breakthrough bleeding

Uncommon/Severe Side Effects

  • Blood clots (symptoms include leg swelling, chest pain, or shortness of breath)
  • Stroke (symptoms include sudden numbness or weakness, trouble speaking, or severe headache)
  • Liver problems (indicated by jaundice, dark urine, or abdominal pain)

Risks and Warnings of Kariva

  • Cardiovascular Risks: The risk of blood clots is higher in women taking combination oral contraceptives, particularly those who smoke or have a history of clotting disorders. Women over 35 who smoke should consider alternative contraceptive options.
  • Liver Health: Regular monitoring of liver function may be necessary in patients with a history of liver disease.
  • Cervical Cancer: Long-term use of hormonal contraceptives may slightly increase the risk of cervical cancer; regular screenings are advised.

Interactions with Kariva

Common Drug Interactions

  • Antibiotics: Certain antibiotics may reduce the effectiveness of Kariva, leading to an increased risk of unintended pregnancy.
  • Antiepileptic drugs: Such as phenytoin and carbamazepine may lower the effectiveness of Kariva.
  • St. John’s Wort: This herbal supplement can also reduce the effectiveness of oral contraceptives.

Alternatives to Kariva

  • Loestrin: Another combination oral contraceptive with different hormone formulations.
  • Ortho Tri-Cyclen: A combination contraceptive that varies hormone levels throughout the cycle.
  • Depo-Provera: A progestin-only injectable contraceptive given every three months.
  • IUDs: Intrauterine devices like Mirena or ParaGard, which provide long-term contraception without daily pills.