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Isuprel

Isuprel, or Isoprenaline, is a medication classified as a bronchodilator and is also used as a heart medication because it increases the heart rate and makes the heart more efficient. It's commonly used for the treatment of certain heart conditions and in emergencies to treat heart block and ventricular fibrillation. However, it can cause side effects like fast heart rate, increased blood pressure, and anxiety, so it's important to use as directed by a healthcare provider.

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Frequently Asked Questions

Can I administer Isuprel to myself?
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Typically, Isuprel is administered by a doctor or nurse in a hospital or emergency.

I have diabetes, can I receive Isuprel?
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This drug can increase blood sugar levels. If you're diabetic, your doctor will likely still administer it during a cardiac emergency, but your blood glucose levels will need to be monitored closely.

Is it safe for pregnant or breastfeeding women?
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There isn't enough information on how Isuprel might affect an unborn baby or a nursing infant. It's safest to consult your doctor if you're pregnant, intending to become pregnant, or breastfeeding.

What should I do if I am having severe side effects?
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If you're experiencing severe side effects like chest pain, difficulty breathing, or signs of allergic reaction, seek immediate medical help.

Comprehensive Drug Guide

How Does Isuprel Work?

Isuprel is a nonselective betaadrenoceptor agonist that mimics the action of adrenaline, leading to positive chronotropic (increasing heart rate) and inotropic (increasing myocardial contractility) effects.

What is Isuprel Used For?

FDA indications: Isuprel is used to treat heart block (interference with the electric signals that stimulate the heart to beat) and during cardiac arrest to reestablish spontaneous rhythm.

Offlabel uses: It might be administered to tackle serious attacks of asthma or bronchospasm when conventional bronchodilators don't work.

Common Dosages

Injection: 1mg/1ml, 5mg/5ml, 20mg/20ml

Typical Dosing

FDA Approved Indications

  • Heart block: Dosage is determined by the doctor based on severity.
  • Cardiac arrest: Standard dosage is 0.5mg to 1mg intravenously.

Off-Label Uses

  • Severe attacks of asthma or bronchospasm: Dosage is determined by the healthcare provider.

Who Shouldn't Take Isuprel?

  • People who have certain heart rhythm disorders.
  • People with a history of heart attacks.
  • People with high blood pressure.
  • People who suffer from thyroid disease.
  • People who have diabetes.
  • Pregnant women or those who are breastfeeding should take this medication with caution and consultation.

Advice From The Pharmacist

  • Isuprel is normally administered by a healthcare provider during a medical emergency.
  • That means it's key to communicate your medical history and any medication you might be taking.
  • If you have any allergies, make sure to let your doctor know.
  • After receiving Isuprel, your heart rate and blood pressure will be closely monitored. Stick around!

Side Effects of Isuprel

Common Side Effects

  • You might feel like your heart is racing.
  • You might feel nervous or anxious.
  • Your hands might start shaking.

Uncommon/Severe Side Effects

  • Uncommon side effects:
  • Dizziness
  • Nausea or vomiting
  • Sweating
  • Rare side effects:
  • Chest pain or discomfort
  • Difficulty breathing
  • Pale skin
  • Severe side effects:
  • Signs of a severe allergic reaction like rash, itching or swelling of face/tongue/throat, severe dizziness, and trouble breathing need immediate medical attention.

Risks and Warnings of Isuprel

  • While Isuprel can revitalize your heart during emergencies, it's not for everyone. People with certain heart rhythm disorders or a history of heart attack should avoid this med.
  • Individuals battling high blood pressure, thyroid disease, or diabetes could face added troubles with Isuprel due to its impact on heart rate and blood sugar.
  • Pregnant women and breastfeeding moms should use it only after due consultation since the effects on the baby aren't fully known.
  • Finally, remember the golden rule: Always let your healthcare provider know about your current medications, underlying health conditions, and allergies before receiving Isuprel.

Interactions with Isuprel

Common Drug Interactions

  • Antidepressants (like amitriptyline, and doxepin)
  • Betablockers (like metoprolol, and atenolol)
  • Antiarrhythmics (like quinidine, flecainide)
  • Thyroid medications
  • Diabetes medications
  • Other bronchodilators

Alternatives to Isuprel

  • Epinephrine
  • Norepinephrine
  • Dopamine
  • Dobutamine