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Isopto Atropine
Isopto Atropine (atropine sulfate) is a muscarinic antagonist used primarily in ophthalmology to induce mydriasis (dilation of the pupil) and to paralyze the ciliary muscle for diagnostic procedures. It can also be used to treat certain eye conditions and is effective in reducing excessive salivation in specific medical contexts.
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Frequently Asked Questions
How long does it take for Isopto Atropine to work?
Isopto Atropine typically starts to cause pupil dilation within 30 minutes of administration, with peak effects occurring around 1 to 2 hours.
Can I take Isopto Atropine with other medications?
Always consult your healthcare provider before combining Isopto Atropine with other medications, especially other eye drops.
What should I do if I miss a dose of Isopto Atropine?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Is it safe to use Isopto Atropine during pregnancy?
Isopto Atropine should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Isopto Atropine cause weight gain?
Weight gain is not a common side effect of Isopto Atropine. Any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Isopto Atropine Work?
Atropine works by blocking the action of acetylcholine at muscarinic receptors in the eye. This inhibition leads to the relaxation of the iris sphincter muscle, causing the pupil to dilate, and paralysis of the ciliary muscle, which facilitates the examination of the retina.
Common Dosages
- Ophthalmic solution: Common concentrations include 1% or 0.5% atropine sulfate.
Typical Dosing
- For mydriasis: The usual dose is 1 to 2 drops in the affected eye(s), administered 30 to 60 minutes prior to the examination.
- For uveitis treatment: The dosage may vary based on the severity of the condition and should be determined by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Inducing mydriasis for ocular examinations.
- Treatment of uveitis and other inflammatory conditions of the eye.
- Management of excessive salivation in certain medical situations.
Who Shouldn't Take Isopto Atropine?
- Known hypersensitivity to atropine or any components of the formulation
- Narrow-angle glaucoma
- Certain types of glaucoma
Advice From The Pharmacist
- Patients should be instructed on the proper technique for administering eye drops to avoid contamination.
- Advise patients that vision may be blurred for several hours after administration, and they should avoid driving or operating machinery until vision is clear.
- Inform patients about potential side effects, including dry mouth, increased heart rate, and sensitivity to light.
Side Effects of Isopto Atropine
Common Side Effects
- Blurred vision
- Dry mouth
- Eye irritation or redness
- Increased heart rate
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis)
- Increased intraocular pressure
Risks and Warnings of Isopto Atropine
- Ocular Effects: Caution should be exercised in patients with pre-existing eye conditions, especially those with glaucoma.
- Systemic Absorption: Atropine can have systemic effects, particularly in high doses or when used in children.
Interactions with Isopto Atropine
Common Drug Interactions
- Other Ophthalmic Agents: Use caution when combining with other eye medications to avoid interactions.
- Anticholinergic Medications: Concurrent use may enhance anticholinergic effects and increase the risk of side effects.
Alternatives to Isopto Atropine
- Other Mydriatic Agents: Such as phenylephrine for similar mydriatic effects.
- Topical Steroids: For managing inflammation in ocular conditions.
